[Hepatoprotective effect of granules of the dry extract obtained from Gentianopsis barbata (Froel) Ma].

Eksp Klin Farmakol

Laboratory of Experimental Pharmacology, Institute of General and Experimental Biology, Siberian Division, Russian Academy of Sciences, ul. Sakh'yanova 6, Ulan-Ude, Buryatia, 670047 Russia.

Published: October 2001

The granulated dry extract from Gentianopsis barbata (Froel) Ma in a dose of 0.1 g/kg produced a pronounced therapeutic effect in rats with experimental toxic (tetrachloromethane) and drug-induced (tetracycline) hepatitis. The gentian extract improved the bile production and secretion functions of liver, normalized the protein, lipid, and pigment metabolism, and increased the antioxidant system activity in the test animals.

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