Regulation of hematopoiesis by chemokine family members.

Int J Hematol

Department of Microbiology and Immunology, Indiana University School of Medicine and the Walther Cancer Institute, Indianapolis 46202-5254, USA.

Published: July 2001

Chemokines, originally designated as chemoattractant cytokines, comprise a large family of molecules that have been implicated in a number of different functions mediated through chemokine receptors. Among these functions are regulatory roles in hematopoiesis that encompass effects on the proliferation, survival, and homing/migration of myeloid progenitor cells. This article reviews the field of chemokine regulation of hematopoiesis at the level of myeloid progenitor cells.

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http://dx.doi.org/10.1007/BF02982544DOI Listing

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