Changes in blood rheology were studied in 106 female hypertensive patients. Basic parameters of blood rheology were recorded: total blood viscosity, plasma viscosity, Hct, erythrocyte aggregation and deformability, fibrinogen, albumin/globulin ratio, and Hct/eta ratio. This set of parameters was presented as the hemorrheological profile. Blood and plasma viscosities were increased in hypertensive patients in comparison with the controls. Therapy with pentoxifylline (600-800 mg/day for 4 weeks) or angiotensin II receptor antagonist losatran (50 mg/day for 4 weeks) resulted in positive changes in the hemorrheological profile.
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