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Treatment of pediatric drug-resistant generalized epilepsy with responsive neurostimulation of the centromedian nucleus of the thalamus: A case series of seven patients.
Epilepsy Res
January 2025
Division of Pediatric Neurology, Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, 8th Floor Faculty Pavilion, 4401 Penn Ave., Pittsburgh, PA 15224, United States. Electronic address:
Purpose: Responsive neurostimulation of the centromedian nucleus of the thalamus (CM RNS) is being investigated for treatment of drug-resistant generalized epilepsy with promising results. The aim of this study is to report outcomes of seven patients with pediatric-onset drug-resistant generalized epilepsy, including both genetic generalized epilepsy (GGE) and Lennox-Gastaut syndrome (LGS), who underwent treatment with bilateral CM RNS.
Methods: A retrospective chart review was performed for patients with drug-resistant generalized epilepsy who underwent treatment with bilateral CM RNS at Children's Hospital of Pittsburgh from 2020 to 2022.
Nursing staffing and skill mix in nursing homes in Italy: An observational cross-sectional study.
Geriatr Nurs
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Ordine delle Professioni Infermieristiche di Bergamo, via Pietro Rovelli 45, Bergamo 24125, Italy.
Introduction/objective: The relationship between staffing levels and skill mix in nursing homes is poorly documented in Italy. This study aimed to investigate nursing staffing levels and skill mix in Northern Italian nursing homes.
Methods: A cross-sectional observational study was conducted using a questionnaire sent to several nursing homes.
Exploring the clinical practice training program for Master of Nursing Specialist in anesthesia: A qualitative study.
Nurse Educ Today
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School of Nursing, Xuzhou Medical University, Xuzhou, Jiangsu, China. Electronic address:
Background: Clinical practice is key in the development and enhancement of the professional competencies for Master of Nursing Specialist postgraduates in anesthesia; however, there is a lack of unified and standardized clinical practice training programs in China, failing to guarantee teaching quality among institutions.
Objective: To understand perceptions of the clinical practice training program setting for Master of Nursing Specialist postgraduates in anesthesia from the dual perspectives of faculty and students.
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Pros and cons of surgical versus conservative management for head and neck paraganglioma: a real-world data analysis.
Endocrine
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Centro di Ricerca e Innovazione sulle Patologie Surrenaliche, AOU Careggi, Florence, Italy.
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Methods: 72 patients with HNPGLs were included. Patients were divided in group A (49 patients undergoing surgery) and group B (23 patients following a wait and see approach).
Perioperative management of postinfarction ventricular septal rupture: a comparison of Impella with intra-aortic balloon pump.
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Saitama Sekishinkai Hospital, 2-37-20 Irumagawa, Sayama, Saitama, Japan.
Postinfarction ventricular septal rupture (PIVSR) is a rare but serious complication of acute myocardial infarction. Determining how to conduct surgical repair safely is critical. We compared the outcomes of Impella and intra-aortic balloon pump (IABP) implantation during perioperative mechanical circulatory support management in patients with PIVSR (n = 22).
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