Type strains of enteroaggregative Escherichia coli EAEC (17-2, serotype O3:H2; JM 221, serotype O92:H33), isolates from an adult and a child with diarrhoea and an asymptomatic colonised child were used to orally infect adult rabbits. The experimental animals were followed up and sacrificed at defined time periods. Colonisation of both small and large intestine was seen with all strains and isolates used. Isolates from an adult patient with diarrhoea (MP 27) and from an asymptomatic colonised child from the community (KM 1337) were recovered from the small intestine during the first week of infection and subsequently from the large intestine. A total of seven rabbits was infected with MP 27; while colonising the gastrointestinal tract of all seven rabbits, this isolate caused diarrhoea in only one. On ultrastructural examination, the rabbits infected with 17-2 showed invasion of lymphoid follicles. Bacteria were seen in intercellular spaces and within M cells, a finding that has not previously been described. It is clearly possible to produce gut colonisation by oral infection with EAEC in adult rabbits with normal flora.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Diarrheagenic Outbreak Reporting to Foodborne Disease Outbreaks Surveillance System - China, 2011-2022.
China CDC Wkly
December 2024
Division of Foodborne Disease Surveillance, China National Center for Food Safety Risk Assessment, Beijing, China.
What Is Already Known About This Topic?: Foodborne diarrheagenic (DEC) outbreaks constitute a significant global public health concern, yet comprehensive data on outbreak incidence and epidemiological characteristics in China remain limited.
What Is Added By This Report?: Between 2011 and 2022, there were 413 foodborne DEC outbreaks reported to foodborne disease outbreak surveillance system, resulting in 8,127 illnesses, 2,565 hospitalizations, and one fatality. Enteroaggregative (EAEC) emerged as the predominant causative pathogen (48.
Detection of diarrhoeagenic Escherichia coli in the abattoir wastewater-impacted Iyi-Etu River and other water types at the Amansea livestock market settlement, Anambra State, Nigeria: a matter of public health concern.
Trans R Soc Trop Med Hyg
January 2025
Department of Microbiology, Kogi State University, P.M.B. 1008 Anyigba, Nigeria.
Background: Globally, diarrhoeagenic Escherichia coli (DEC) has been implicated in the spread of waterborne diseases and abattoir wastewater has played a role in its dissemination into watersheds. This study isolated and characterised DEC from the abattoir wastewater-impacted Iyi-Etu River and other water sources at the Amansea livestock market settlement.
Methods: A total of 96 water samples comprising river water (upstream, downstream 1, downstream 2), borehole, well, sachet and abattoir wastewater samples were tested for DEC.
Escherichia coli in diarrhoeic lambs: Prevalence, virulence and antibiotic resistance.
Pol J Vet Sci
September 2024
Department of Veterinary Microbiology, College of Veterinary and Animal Science, Navania, Vallabhnagar, Udaipur, Rajasthan University of Veterinary and Animal Sciences (RAJUVAS), Rajasthan, India.
The present study aimed to detect the prevalence, virulence and antimicrobial resistance genes profile of Escherichia coli isolated from diarrhoeic lambs. A total of 61 faecal samples were collected from diarrhoeic lambs. The presence of various virulence and antimicrobial resistance genes in E.
View Article and Find Full Text PDFDetection of bla, bla, bla, and bla genes of antibiotic resistance in diarrheagenic E. coli causing enteric infection in hypertensive patients at Laquintinie Hospital, Littoral Region of Cameroon.
J Infect Public Health
January 2025
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon. Electronic address:
Article Synopsis
- Pathogenic Escherichia coli is a leading cause of diarrhea globally, and this study investigates how virulence genes and antibiotic resistance differ in hypertensive versus non-hypertensive patients.* -
- Researchers analyzed 518 fecal samples from patients in Douala, discovering that certain strains like enteropathogenic E. coli (EPEC) were more common in hypertensive individuals, while enteroaggregative E. coli (EAEC) predominated in non-hypertensives.* -
- The study found high resistance rates of E. coli to antibiotics, especially amoxicillin and sulfamethoxazole-trimethoprim, with a significant prevalence of extended-spectrum β-lactamase-producing strains (
Prevalence and Antimicrobial Susceptibility of Foodborne Pathogens from Raw Livestock Meat in China, 2021.
Microorganisms
October 2024
NHC Key Laboratory of Food Safety Risk Assessment, Chinese Academy of Medical Science Research Unit (2019RU014), China National Center for Food Safety Risk Assessment, Beijing 100022, China.
Article Synopsis
- - The study assesses pathogenic bacteria prevalence in raw livestock meat (pork, beef, mutton) in China for 2021, with a focus on antimicrobial resistance (AMR) to inform public health and food safety practices.
- - Out of 2,515 meat samples, contamination rates were highest in pork for certain pathogens, with specific prevalence noted in chilled and frozen meat compared to fresh.
- - The study found high overall resistance rates in bacteria isolated from meat, with ampicillin and tetracycline showing the most significant resistance among the tested antimicrobial agents.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!