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The effects of occupational aluminum exposure on blood pressure and blood glucose in workers - A longitudinal study in northern China.

Toxicol Lett

January 2025

Sinopharm Tongmei General Hospital, Shanxi Health Commission Key Laboratory of Nervous System Disease Prevention and Treatment, Datong, Shanxi 037003, China. Electronic address:

Background: Trace element and metal exposure is closely related to the occurrence of chronic diseases, particularly affecting blood pressure and blood glucose. Current studies suggest that heavy metal exposure is a risk factor for hypertension and diabetes. Aluminum can enter the human body through daily life and occupational exposure from food, environment, drugs, and other sources, affecting the cardiovascular, endocrine, and other systems.

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Objective: Silicosis is a pneumoconiosis characterized by fibrosis of the lung parenchyma caused by the inhalation of silica particles. Silica dust inhalation is associated with inflammation and induction of oxidative stress in the lungs. This oxidative stress affects telomeres, which are short tandem DNA repeats that cap the end of linear chromosomes.

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Introduction: Pneumoconiosis represents the most prevalent occupational disease in China, with coal workers' pneumoconiosis (CWP) showing the highest incidence. Analysis of volatile organic compounds (VOCs) in the exhaled breath of CWP patients may provide novel insights into its pathogenesis.

Methods: Study data were collected through questionnaires and medical examinations.

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Pneumoconiosis is the occupational disease with the highest proportion in China. This study conducted a retrospective analysis of 5,791 deceased pneumoconiosis patients. In this study, males comprised 93.

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Coal Worker's Pneumoconiosis-Targeted Lipidomics Reveals Aberrant Phospholipid Metabolism for Early-Stage Diagnosis.

China CDC Wkly

December 2024

NHC Key Laboratory of Pneumoconiosis, MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Key Laboratory of Respiratory Diseases, The First Hospital of Shanxi Medical University, Taiyuan City, Shanxi Province, China.

Introduction: Pneumoconiosis is the most prevalent occupational disease in China, with coal worker pneumoconiosis (CWP) demonstrating the highest incidence. Studies have indicated that phospholipids may be associated with CWP.

Methods: In this study, serum was obtained from 62 patients with pneumoconiosis, 105 coal dust-exposed workers, and 50 healthy individuals and analyzed via targeted lipidomics using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).

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