The objective was to determine normative values for tympanometric variables for 7- and 24-month-old children and to assess the effect of various factors on these variables. Tympanometry was performed at scheduled health visits at 7 and 24 months of age on children recruited to a prospective vaccine efficacy trial (n=2497 children at enrolment). Tympanograms obtained successfully from healthy ears with no recent otitis media were analysed. Normative values for static acoustic admittance (SAA), tympanometric peak pressure (TPP) and tympanometric width (TW) were calculated. The mean SAA was 0.25 cm3 at the 7-month visit compared to 0.34 cm3 at the 24-month visit. The TW decreased and TPP remained unchanged with age. Higher SAA values were found in boys. A history of recurrent acute otitis media and history of tympanostomy tubes were found to increase SAA and decrease TW at 24 months. In conclusion, age-specific normative values for interpretation of SAA and TW are necessary.
Download full-text PDF |
Source |
---|
Artif Intell Med
January 2025
Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy; Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
The heterogeneity of psychiatric disorders makes researching disorder-specific neurobiological markers an ill-posed problem. Here, we face the need for disease stratification models by presenting a generalizable multivariate normative modelling framework for characterizing brain morphology, applied to bipolar disorder (BD). We used deep autoencoders in an anomaly detection framework, combined for the first time with a confounder removal step that integrates training and external validation.
View Article and Find Full Text PDFPalliat Med
January 2025
Department of Health Sciences, University of York, York, UK.
Background: Delirium is common and distressing for hospice in-patients. Hospital-based research shows delirium may be prevented by targeting its risk factors. Many preventative strategies address patients' fundamental care needs.
View Article and Find Full Text PDFCureus
December 2024
Department of Otolaryngology, Head and Neck Surgery, Wrightington, Wigan and Leigh NHS Foundation Trust, Wigan, GBR.
Objectives To assess the dimensions of external ear (pinna) in different age groups in the North Indian population. To assess the mean dimensions of external ear (pinna) in different age groups in North Indian males and females. Methods The study area was Lucknow/Barabanki, Uttar Pradesh, and the study center was Era's Lucknow Medical College, Uttar Pradesh, India.
View Article and Find Full Text PDFEur J Neurol
January 2025
AIMS Lab, Center for Neurosciences, Vrije Universiteit Brussel, Elsene, Brussels, Belgium.
Background And Purpose: Cognitive impairment in multiple sclerosis (MS) is common and is associated with problems in employment, driving ability, and quality of life. Since cognitive impairment at time of diagnosis is predictive of disability progression, early assessment and annual monitoring is recommended. The Brief International Cognitive Assessment in Multiple Sclerosis (BICAMS) was introduced as a time-efficient screening tool that can easily be applied in standard clinical care.
View Article and Find Full Text PDFMuscle Nerve
January 2025
Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA.
Introduction/aims: The standard procedure to establish reference values in a neuromuscular laboratory involves examining healthy controls, as nerve size varies with the population and muscle echo intensity (EI) is device-specific. We aimed to derive these reference values by extrapolation from a studied sample (the e-norms method), compare them with published reference values, and determine their diagnostic accuracy.
Methods: We retrospectively analyzed data from consecutive patients who underwent nerve and/or muscle ultrasound in our ultrasound laboratory, which is a tertiary referral center for neuromuscular diseases in Southern Poland in the years 2018-2023.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!