Method of combined radiotherapy of choroid melanomas, proposed by the authors, includes transscleral irradiation of the tumor by rutenium ophthalmoapplicators and simultaneous intracorporeal irradiation with 59Fe. Twenty-seven patients were treated. Morphological examination of enucleated eyes showed the capacity of 57Fe to incorporate in tumor cell, and observations indicate that this method of treatment not only extends the indications for organ-sparing radiotherapy of uveal melanomas, but delays the development of distant metastases as well.

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