Objective: The aim of this study was to investigate whether there were differences in amplitude and latency among the different waveform patterns of sympathetic skin response (SSR) in diabetic patients. The authors also investigated whether the proportion of the SSR waveform patterns was influenced by diabetic polyneuropathy (DP), symptoms of dysautonomia, and impaired R-R interval variation of the heart rate.
Design/methods: Twenty SSRs from palm skin were analyzed in 53 diabetic patients and 45 normal subjects. Waveforms were classified as either the P type, in which the positive component was larger than the negative one, or the N type, in which the negative component was larger than the positive one. The patterns of occurrence in these two waveform types were classified into 3 kinds, i.e. P, N, and M patterns. In the P and N patterns, all the SSRs were of the P and N types, respectively. The M pattern had both P and N types during consecutive recordings.
Results: The patients' age and glycosylated hemoglobin values did not differ among the 3 SSR patterns. The P pattern, however, had a larger amplitude and shorter latency than the N pattern, just as previously reported in a normal population. The distribution of the SSR patterns in diabetic patients was not statistically different from that in the normal controls, and it was not influenced by the DP, symptoms of dysautonomia, or impaired R-R interval variation of the heart rate.
Conclusions: The distribution of the SSR waveform patterns was not influenced by the pathological conditions related to diabetes. It might be advised to confirm the balanced distribution of the SSR waveform patterns in patient and control groups before comparing the values of amplitude and latency between the two groups.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/s1388-2457(01)00569-7 | DOI Listing |
BMC Med
January 2025
Department of Health Economics, School of Public Health, Fudan University, Shanghai, China.
Background: Adolescent diabetes is one of the major public health problems worldwide. This study aims to estimate the burden of type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in adolescents from 1990 to 2021, and to predict diabetes prevalence through 2030.
Methods: We extracted epidemiologic data from the Global Burden of Disease (GBD) on T1DM and T2DM among adolescents aged 10-24 years in 204 countries and territories worldwide.
Diabetol Metab Syndr
January 2025
Department of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, No.666 Shengli Road, Nantong, 226001, China.
Background: Increased glucagon levels are now recognized as a pathophysiological adaptation to counteract overnutrition in type 2 diabetes (T2D). This study aimed to elucidate the role of glucagon in peripheral nerve function in patients with T2D with different body mass indices (BMIs).
Methods: We consecutively enrolled 174 individuals with T2D and obesity (T2D/OB, BMI ≥ 28 kg/m), and 480 individuals with T2D and nonobesity (T2D/non-OB, BMI < 28 kg/m), all of whom underwent oral glucose tolerance tests to determine the area under the curve for glucagon (AUC).
BMC Cancer
January 2025
Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 West 5th Road, Xi'an, Shaanxi, 710004, China.
Background: Anthracycline usage has been linked to cardiovascular adverse events (CAEs), which is unpredictable. It is critical to identify the characteristics of vulnerable populations and risk factors in order to reduce the occurrence of CAEs.
Objectives: This meta-analysis aimed to assess the correlation between various risk factors and CAEs induced by anthracyclines.
BMC Infect Dis
January 2025
Department of Dermatology, Showa University School of Medicine, 1-5-8, Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.
Background: Cytomegalovirus (CMV) can cause life-threatening diseases in immunosuppressed patients. Some of the patients with connective tissue disease develop CMV infection, and approximately half of this group has been reported to have received pulsed-methylprednisolone (p-MPSL) therapy. This study aimed to identify predictors of the onset of CMV infection in patients receiving p-MPSL therapy for connective tissue disease.
View Article and Find Full Text PDFBMC Cardiovasc Disord
January 2025
The second Affiliated Hospital of Xi'an Jiaotong University, Xinjiang Hospital (People's Hospital of Xinjiang Uygur Autonomous Region, Bainiaohu Hospital), Urumqi, Xinjiang, 830026, People's Republic of China.
Background: Several studies showed higher risks of cardiovascular complications to have been observed in patients with type 2 diabetes mellitus (T2DM). Atrial fibrillation (AF) and atrial flutter have been more pronounced in patients with hyperglycemia. Sodium-glucose co-transporter 2 (SGLT2) inhibitors are now considered as second-line treatment for patients with T2DM following inadequate glycemic control with first line agents.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!