Blood samples from 243 clean-up workers who undertook duties at Chernobyl in 1986 were examined in order to study temporal changes of chromosomal aberrations over long periods (6-12 yr) following irradiation. From an analysis of the elapsed time between irradiation and cytogenetic examination, it was found that the frequency of dicentrics and rings did not decrease during the 6 yr period of observation.
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http://dx.doi.org/10.1016/s0969-8043(01)00059-8 | DOI Listing |
J Expo Sci Environ Epidemiol
December 2024
Department of Epidemiology, UNC Gillings School of Public Health, Chapel Hill, NC, USA.
Background: Despite evidence from experimental studies linking some petroleum hydrocarbons to markers of immune suppression, limited epidemiologic research exists on this topic.
Objective: The aim of this cross-sectional study was to examine associations of oil spill related chemicals (benzene, toluene, ethylbenzene, xylene, and n-hexane (BTEX-H)) and total hydrocarbons (THC) with immune-related illnesses as indicators of potential immune suppression.
Methods: Subjects comprised 8601 Deepwater Horizon (DWH) oil spill clean-up and response workers who participated in a home visit (1-3 years after the DWH spill) in the Gulf Long-term Follow-up (GuLF) Study.
Probl Radiac Med Radiobiol
December 2024
State Institution «National Research Center for Radiation Medicine, Hematology and Oncology of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka Str., Kyiv, 04050, Ukraine.
The objective was to study the relationship between clinical symptoms and the functional state of the bronchopulmonary system of clean-up workers of the Chornobyl Nuclear Power Plant accident with chronic obstructive pulmonary disease in the remote post-accident period.Materials and methods. A retrospective analysis of 824 cases of COPD in male patients who underwent inpatienttreatment in the radiation pulmonology department from 2014 to 2024 was conducted.
View Article and Find Full Text PDFProbl Radiac Med Radiobiol
December 2024
State Institution «National Research Center for Radiation Medicine, Hematology and Oncology of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka Str., Kyiv, 04050, Ukraine.
Unlabelled: Problem of the causal relationship of disease that became the reason of death with the effect of ionizing radiation and due to harmful influence of the Chornobyl Catastrophe during performance of professional, military or official duties and / or living on radiation-contaminated areas, additional exposure not through their own fault but due to a radiation accident, caused the development of a special form of medical expertise as part of the of medical social protection system for suffered contingents in the remote postaccidental period.
Objective: To study and characterize the structure of the survivor categories (clean-up workers and victims) of the Chernobyl Catastrophe in the remote post-accident period (2013-2024) regarding the causal relationship of disease that became the reason of death with the effect of ionizing radiation and due to harmful influence of the Chornobyl Catastrophe based on the materials of expert cases of the Central Interdepartmental Expert Commission of the Ministry of Health of Ukraine (CIEC).
Material And Methods: The work was performed in the design of a retrospective study that based on analysis of the structure of all categories of Chornobyl NPP accident (ChNPP) survivors during 2008-2024 years and studying of 58,137 medical expert cases, including 19,524 postmortem cases, which were considered by CIEC during 2013-2023 to establish a causal relationship between the disease and influence of radiation exposure and other harmful factors and conditions during ChNPP accident.
Probl Radiac Med Radiobiol
December 2024
State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka Str., Kyiv, 04050, Ukraine.
Objective: to study the features of cognitive disorders in the remote period following exposure to ionizing radiation (IR) in the elderly participants of the liquidation of the consequences of the Chornobyl NPP accident (Chornobyl clean-up workers) with chronic cerebrovascular disorders.
Materials And Methods: The retrospective and prospective cohort study with the external and internal controlgroups. The randomized sample of the male elderly participants (attained age more than 60 years old) in liquidationof the consequences of the accident (Chornobyl clean-up workers, liquidators) at the Chornobyl nuclear power plant(ChNPP) in 1986-1987 (main group, n = 52) recruited from the Clinico-epidemiological registry (CER) of StateInstitution «National Research Center for Radiation Medicine, Hematology and Oncology of The National Academyof Medical Sciences of Ukraine» (NRCRMHO) with verified chronic cerebrovascular disorders (CVD) was examined.
Probl Radiac Med Radiobiol
December 2024
State Institution «National Research Center for Radiation Medicine, Hematology and Oncology of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka Str., Kyiv, 04050, Ukraine.
Objective: To assess the functional state and age-related characteristics of autophagy in peripheral blood leukocytes as a risk factor for the development of inflammaging using the example of the servicemen of the DefenseForces of Ukraine and clean-up workers of the Chornobyl accident.
Materials And Methods: A total of 103 male patients aged 28-77 (56,48 ∓ 9,05) years were examined. They included: the main group - 23 servicemen of the Defense Forces of Ukraine aged 44-59 (50,21 ∓ 5,13) years; the comparison group - 57 clean-up workers of the Chornobyl accident aged 56-63 (60,31 ∓ 1,78) years; and the control group -23 civilians aged 28-77 (53,26 ∓ 15,98) years.
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