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Turning the Tide of Viral Hepatitis-Induced Acute Liver Failure: The Role of Standard Volume Plasma Exchange in Adults and Children.
Transfus Clin Biol
January 2025
Department of Immunohematology and Blood Transfusion, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun 248140 Uttarakhand, India.
Introduction: Therapeutic plasma exchange (TPE) is the most widely used artificial liver support system in liver failure patients.
Cases: We report five cases of viral hepatitis induced ALF 3 adult (case I, II, III) and two pediatric (case IV and V) patients not adequately responding to standard medical treatment (SMT). Case I and II were acute hepatitis B infections while case III was an antenatal case with acute hepatitis E.
Multi-omics characterization and machine learning of lung adenocarcinoma molecular subtypes to guide precise chemotherapy and immunotherapy.
Front Immunol
December 2024
Department of Anesthesiology, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu, China.
Background: Lung adenocarcinoma (LUAD) is a heterogeneous tumor characterized by diverse genetic and molecular alterations. Developing a multi-omics-based classification system for LUAD is urgently needed to advance biological understanding.
Methods: Data on clinical and pathological characteristics, genetic alterations, DNA methylation patterns, and the expression of mRNA, lncRNA, and microRNA, along with somatic mutations in LUAD patients, were gathered from the TCGA and GEO datasets.
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Lancet Reg Health Eur
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