The paper proposes that for more reliable resection of cancer tumors and involved biological tissues during a surgical intervention, the structure of biological tissues should be evaluated by measuring its impedance at two frequencies: 2 and 440 KHz and by calculating the polarization coefficient (Cpolar). Examining Cpolar changes in intact and pathologically altered biological tissues allowed them to be distinguished during a surgical intervention by employing an impedance electrosurgical apparatus.
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Vasc Biol
January 2025
K Landers, Psychology, University of Arkansas at Little Rock, Little Rock, United States.
Blood flow restriction exercise (BFRE) is a therapeutic approach traditionally used to facilitate muscular strength and hypertrophy. Emerging evidence has identified its benefits on other systems and metabolic processes. The emphasis of this study was to examine potential impact of BFRE on serum levels of tissue plasminogen activator (tPA).
View Article and Find Full Text PDFCrit Care Explor
February 2025
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Objectives: Sepsis is a life-threatening medical emergency, with a profound healthcare burden globally. Its pathophysiology is complex, heterogeneous and temporally dynamic, making diagnosis challenging. Medical management is predicated on early diagnosis and timely intervention.
View Article and Find Full Text PDFFish Physiol Biochem
January 2025
Centro Tlaxcala de Biología de La Conducta, Universidad Autónoma de Tlaxcala, 90070, Tlaxcala, Mexico.
Trophic factors, such as neurotrophins, are fundamental for cellular processes including differentiation, growth, survival, and regeneration. These molecules exhibit significant morphological and phylogenetic conservation throughout the animal kingdom, indicating conserved functions. In fish, the oldest and most diverse group of vertebrates, neurotrophins, and their receptors play pivotal roles not only within the central nervous system but also in various peripheral tissues.
View Article and Find Full Text PDFEur J Nucl Med Mol Imaging
January 2025
AIDS Imaging Research Section, Division of Clinical Research, NIAID, NIH, Poolesville, MD, USA.
Purpose: Following the initial reports demonstrating the feasibility of immunoPET imaging of simian immunodeficiency virus (SIV) using gp120-targeting monoclonal antibodies in non-human primates, replication efforts of the imaging system in human immunodeficiency virus (HIV)-infected individuals have yielded conflicting results. Herein, we used two anti-gp120 antibodies, 7D3 and ITS103.01LS-F(ab'), to interrogate the reproducibility of gp120-targeting probes for immunoPET imaging of SIV in rhesus macaques.
View Article and Find Full Text PDFJ Gastroenterol
January 2025
School of Medicine, Anhui University of Science & Technology, Huainan, China.
Background: Liver cirrhosis represents a critical stage of chronic liver disease, characterized by progressive liver damage, cellular dysfunction, and disrupted cell-to-cell interactions. Glycosylation, an essential post-translational modification, significantly influences cellular behavior and disease progression. Its role in cirrhosis at the single-cell level remains unclear, despite its importance.
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