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Provision of Mental and Behavioral Health Supports and Services by Pharmacists in Washington State.
Community Ment Health J
January 2025
Department of Pharmacy, University of Washington School of Pharmacy, 1959 NE Pacific Street, Box 357630, Seattle, WA, 98195, USA.
Pharmacists are highly accessible healthcare professionals with presence in communities, hospitals, and clinics. They are well positioned to expand their roles in supporting individuals with mental health challenges. A cross-sectional study was conducted to identify trends in how pharmacists assess, monitor, identify, and care for patients with mental health challenges.
View Article and Find Full Text PDFBasic Science and Pathogenesis.
Alzheimers Dement
December 2024
Medical University of South Carolina, Charleston, SC, USA.
Background: Specialized pro-resolving mediators (SPMs) promote inflammatory resolution and homeostasis and are thought to have specific reprogramming effects on hman microglia. Decreased SPM levels have been correlated with chronic neuroinflammation, late-stage Alzheimer's disease (AD) and neuropathology in humans, yet few studies have explored the cellular signatures of resolution. Amyloid is though to bind one target resolution receptor, ChemR23, leading to internalization.
View Article and Find Full Text PDFThe Physical Activity at Work (PAW) Program in Thai Office Workers: Mixed Methods Process Evaluation Study.
JMIR Form Res
January 2025
Health Intervention and Technology Assessment Programme, Ministry of Public Health, Nonthaburi, Thailand.
Background: An increasing number of multicomponent workplace interventions are being developed to reduce sedentary time and promote physical activity among office workers. The Physical Activity at Work (PAW) trial was one of these interventions, but it yielded an inconclusive effect on sedentary time after 6 months, with a low uptake of movement breaks, the main intervention component.
Objective: This study investigates the factors contributing to the outcomes of the PAW cluster randomized trial.
Evaluation and Improving the Quality of Arterial Blood Gas Interpretation Among Junior Doctors in Aswan University Hospital: A Clinical Audit.
Cureus
December 2024
Pulmonary Medicine, Aswan University Hospitals, Aswan, EGY.
Article Synopsis
- Arterial blood gas (ABG) analysis is crucial for diagnosing critical conditions in patients, and misinterpretation can lead to serious management issues.
- A study conducted at Aswan University Hospitals involved 273 healthcare professionals and assessed their ABG interpretation skills before and after targeted educational interventions over two weeks.
- Results indicated significant improvements, with accuracy in interpreting ABG results increasing from 71.8% to 90.2% and enhanced skills in identifying acid-base disturbances and distinguishing between respiratory and metabolic issues.
Self-Delivering RNAi Compounds for Reduction of Hyperpigmentation.
Clin Cosmet Investig Dermatol
December 2024
Phio Pharmaceuticals, Marlborough, MA, USA.
Purpose: Abnormal melanin synthesis causes hyperpigmentation disorders like melasma and lentigines, impacting psychological well-being. RNA interference (RNAi) uses small RNA molecules to inhibit gene expression by targeting specific mRNA, silencing genes involved in undesirable cellular functions. This study assessed INTASYL compounds, self-delivering RNAi molecules, designed to target and reduce tyrosinase gene expression to decrease pigmentation.
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