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The paper characterizes the clinical and laboratory indices of the endogenous intoxication syndrome (EIS) in 173 patients with acute Russian tick-borne encephalitis. In its feverish form, EIS is characterized by the general intoxication syndrome and a slight increase in the luciferase index (LI). In its meningeal form, EIS is accompanied by overall cerebral symptoms, cardiovascular, respiratory and hepatic detoxifying dysfunctions, which are manifested by increases in both the intoxication leukocyte index of (ILI) and LI. In its focal form, EIS is characterized by the signs of multiorgan failure with the most pronounced alterations in the laboratory indices of endotoxemia (LID and LI).
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