A linear filter was developed for decoding finger commands from volitional pressures distributed within the residual forelimb. Filter parameters were based on dynamic pressures recorded from the residual limb within its socket, during specific finger commands. A matrix of signal features was derived from eight-dimensional (8-D) pressure vectors, and its pseudoinverse comprised the filter parameters. Results with amputees showed that the filter could discriminate specific finger flexion commands, suggesting that pressure vector decoding (PVD) can provide them with biomimetic finger control.
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http://dx.doi.org/10.1109/7333.918278 | DOI Listing |
J Biomed Opt
June 2024
Food and Drug Administration, Center for Devices and Radiological Health, Silver Spring, Maryland, United States.
Significance: Pulse oximeter measurements are commonly relied upon for managing patient care and thus often require human testing before they can be legally marketed. Recent clinical studies have also identified disparities in their measurement of blood oxygen saturation by race or skin pigmentation.
Aim: The development of a reliable bench-top performance test method based on tissue-simulating phantoms has the potential to facilitate pre-market assessment and the development of more accurate and equitable devices.
Biomimetics (Basel)
December 2024
Institute of Instrument Science and Engineering, Southeast University, Nanjing 210096, China.
Soft Robot
December 2024
Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea.
High-performance eco-friendly soft actuators showing large displacement, fast response, and long-term operational capability require further development for next-generation bioinspired soft robots. Herein, we report an electro-ionic soft actuator based on carboxylated cellulose nanocrystals (CCNC) and carboxylated cellulose nanofibers (CCNF), graphene nanoplatelets (GN), and ionic liquid (IL). The actuator exhibited exceptional actuation performances, achieving large displacements ranging from 1.
View Article and Find Full Text PDFCommun Eng
November 2024
Department of Mechanical Engineering, University of Victoria, 3800 Finnerty Road, Victoria, V8P 5C2, BC, Canada.
Non-physiological levels of oxygen and nutrients within the tumors result in heterogeneous cell populations that exhibit distinct necrotic, hypoxic, and proliferative zones. Among these zonal cellular properties, metabolic rates strongly affect the overall growth and invasion of tumors. Here, we report on a hybrid discrete-continuum (HDC) mathematical framework that uses metabolic data from a biomimetic two-dimensional (2D) in-vitro cancer model to predict three-dimensional (3D) behaviour of in-vitro human glioblastoma (hGB).
View Article and Find Full Text PDFBMC Med
November 2024
Department of Histology, Tissue Engineering Group, School of Medicine, University of Granada, Granada, Spain.
Background: Human artificial corneas (HAC) generated by tissue engineering recently demonstrated clinical usefulness in the management of complex corneal diseases. However, the biological mechanisms associated to their regenerative potential need to be elucidated.
Methods: In the present work, we generated HAC using nanostructured fibrin-agarose biomaterials with cultured corneal epithelial and stromal cells, and we compared the structure and histochemical and immunohistochemical profiles of HAC with control native corneas (CTR-C) and limbus (CTR-L) to determine the level of biomimicry of the HAC with these two native organs.
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