Effect of a six month gemfibrozil treatment and dietary recommendations on the metabolic risk profile of visceral obese men.

Int J Obes Relat Metab Disord

Physical Activity Sciences Laboratory, Division of Kinesiology, Department of Social and Preventive Medicine, Faculty of Medicine, Laval University, Québec, Canada.

Published: August 2001

Objective: The aim of the present study was to investigate the effects of a 6 month gemfibrozil treatment.

Subjects: A sample of 64 visceral obese men (age 46+/-6 y; body mass index 31+/-3 kg/m(2); waist circumference 104+/-7 cm; mean+/-s.d.) who received dietary recommendations.

Methods: Subjects were randomly assigned to receive a placebo (n=32) or gemfibrozil (1200 mg/day) (n=32).

Results: In both placebo and gemfibrozil treated groups, significant reductions were noted in body weight, fat mass, waist circumference and visceral adipose tissue area measured by computed tomography (0.0001

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http://dx.doi.org/10.1038/sj.ijo.0801665DOI Listing

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