Purpose: To describe the first case of intraocular teratoma associated with eyelid coloboma and the second reported case of intraocular teratoma.
Design: Interventional case report.
Methods: A left intraocular tumor was surgically resected from a 2-day-old female with an associated lower eyelid coloboma.
Results: Pathologic evaluation revealed a completely intraocular tumor comprising derivatives of all three germ cell layers giving a diagnosis of intraocular teratoma. The eyelid coloboma was repaired, and a scleral-wrapped hydoxyapatite-integrated orbital implant was placed.
Conclusion: To our knowledge, this is the second reported instance of teratoma originating within the globe and the only reported case of teratoma associated with eyelid coloboma. Although exceedingly rare, intraocular teratoma should be added to the differential diagnosis of congenital intraocular tumors.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0002-9394(01)00827-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ciliary Body Medulloepithelioma: Clinical and Pathologic Challenges with a Focus on Molecular Genetics.
Semin Ophthalmol
January 2025
Department of Ophthalmology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.
Objective: Ciliary body medulloepithelioma (CBME), a pediatric intraocular tumor with potential for locally aggressive behavior and metastasis, may present with a diverse spectrum of clinical and histopathologic features leading to diagnostic and management challenges. Examination of unusual CBME cases highlights challenges and modern diagnostic techniques which facilitate accurate diagnosis and guide management.
Methods: A retrospective clinicopathologic analysis of 6 patients with unusual clinical or pathologic features of CBME was performed.
Ocular and orbital tumors in childhood.
Clin Dermatol
July 2024
Department of Dermatology, University of Connecticut School of Medicine, Farmington, Connecticut, USA; Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida, USA. Electronic address:
Article Synopsis
- * Most pediatric eye tumors, like dermoid cysts and chalazia, are benign but can still cause serious health issues due to their location.
- * Key types of pediatric eye tumors include vascular lesions, retinoblastoma, rhabdomyosarcoma, Langerhans cell histiocytosis, and certain metastatic lesions like neuroblastoma.
Preoperative geometric parameters predict the outcome of lamellar keratoscleroplasty in patients with limbal dermoids.
Int Ophthalmol
July 2023
Joint Shantou International Eye Center of Shantou University, The Chinese University of Hong Kong, Dongxia Road, Shantou, 515041, Guangdong Province, People's Republic of China.
Article Synopsis
- The study aimed to identify simple geometric parameters that can predict the surgical outcomes of lamellar keratoscleroplasty in patients with corneal limbal dermoids.
- A total of 30 patients were analyzed, focusing on seven specific geometric metrics related to the dermoid and their impact on postoperative visual acuity, astigmatism, and scarring.
- Key findings indicated that the length of the dermoid invading the cornea was significantly associated with both improved visual acuity and astigmatism after surgery, especially in patients with amblyopia.
Removal of a congenital corneal dermoid through tumor excision and lamellar keratoplasty in a young child: A case report.
Medicine (Baltimore)
December 2021
Department of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Rationale: Corneal dermoids are a rare cause of corneal opacification, consisting of abnormal mesoblastic tissue surrounded by epithelium. Here, we describe the case of a 1-year-old child who had a congenital corneal dermoid in the left eye since birth; thus, the patient underwent tumor excision followed by keratoplasty.
Patient Concern: A 1-year-old girl was brought to the hospital by her parents, who had been noticing a mass on the surface of her left eyeball since birth.
Factors predicting long-term changes in refraction after lamellar keratoscleroplasty in children with limbal dermoids.
Eye (Lond)
June 2021
Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.
Objectives: The objective of this study is to determine the factors that predict long-term changes in refraction after lamellar keratoscleroplasty in paediatric patients with limbal dermoids.
Methods: A retrospective study of 66 children with limbal dermoids who had lamellar keratoscleroplasty correction with more than 1-year follow-up. Univariate and multivariate regression analyses were performed to investigate factors associated with the long term in refractive parameters, including spherical equivalent, astigmatism, and mean keratometry.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!