[Functions of the 'Therapeutic Drug Monitoring (TDM)' Group of the French Society of Pharmacology].

Therapie

Service de Pharmacologie et Toxicologie, CHU Dupuytren, 2 avenue Martin Luther King, 87042 Limoges, France.

Published: September 2001

Therapeutic Drug Monitoring consists of sampling organization, measurement and interpretation of the blood concentration or biological effect of a given xenobiotic, and sometimes using this result for pharmacokinetic computation, with the aim of individual dose adjustment. This branch of pharmacology is represented internationally by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) and has been organized, in France, as a working group of the French Society of Pharmacology (SFP). This group takes part in the main French organizations dealing with or using TDM, as well as the scientific activities of SFP and organizes multi-centre clinical trials studying exposure-effect relationships or based on 'concentration-controlled' protocols. Finally, another aim of this TDM group is to promote the development and acknowledgement of this activity in hospitals.

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