Mulberry leaves treated with UV-C were found to accumulate three different phytoalexins, moracin C, moracin N, and chalcomoracin. The increased level of malondialdehyde in UV-treated leaves along with moracins suggested their role as a free-radical scavenger in stressed plants. All the three moracins induced under UV stress were capable of scavenging the superoxide anion generated by the xanthine-xanthine oxidase system. Also, moracins were capable of inhibiting lipid peroxidation, which strongly indicates their role as a scavenger.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1271/bbb.65.1402 | DOI Listing |
J Pharm Anal
June 2024
Cancer Center, Department of Medical Oncology, Key Laboratory of Tumor Molecular Diagnosisand Individualized Medicine of Zhejiang Province, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China.
Lung cancer ranks the top of malignancies that cause cancer-related deaths worldwide. The leaves of L are traditional Chinese medicine widely applied in respiratory diseases. Our previous work has demonstrated the anti-lung cancer effect of secondary metabolites of mulberry leaf, but their mechanism of action has still not fully elucidated.
View Article and Find Full Text PDFPhytomedicine
June 2024
State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China; Jinfeng Laboratory, Chongqing 401329, China; Chongqing Engineering and Technology Research Center for Silk Biomaterials and Regenerative Medicine, Chongqing 400716, China. Electronic address:
Background: Pancreatic cancer, a tumor with a high metastasis rate and poor prognosis, is among the deadliest human malignancies. Investigating effective drugs for their treatment is imperative. Moracin D, a natural benzofuran compound isolated from Morus alba L.
View Article and Find Full Text PDFFront Pharmacol
February 2024
Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria.
Diabetes remains an important disease worldwide with about 500 million patients globally. In tropical Africa, is traditionally used in the treatment of diabetes. Biological and phytochemical investigation of the root bark extracts of the plant led to the isolation of a new prenylated arylbenzofuran named 7-(3-hydroxy-3-methylbutyl)moracin M () and two congeners, moracins P () and M ().
View Article and Find Full Text PDFJ Asian Nat Prod Res
June 2024
Natural Product Research Group, Organic Chemistry Division, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung, Indonesia.
Three Diels-Alder type adducts (-) along with their precursors, including one 2-arylbenzofuran () and one stilbene (), were isolated from the MeOH extract of var. root cultures. Among them, is a new Diels-Alder type adduct named morushalunin D.
View Article and Find Full Text PDFInt J Mol Sci
January 2024
State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.
Gastrointestinal cancers are a major global health challenge, with high mortality rates. This study investigated the anti-cancer activities of 30 monomers extracted from L. (mulberry) against gastrointestinal cancers.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!