[Liver transplantation in a patient with hemophilia A and end stage liver failure].

Ann Fr Anesth Reanim

Département d'anesthésie-réanimation chirurgicale, hôpitaux universitaires de Strasbourg, hôpital civil, 1, place de l'Hôpital, 67000 Strasbourg, France.

Published: June 2001

We report the case of a 50 year-old man factor VIII deficient haemophiliac and hepatitis C cirrhosis. The patient underwent orthotopic liver transplantation because of episodes of variceal bleeding and encephalopathy. He received factor VIII replacement therapy perioperatively. Factor VIII returned to normal within 24 hours postoperatively and factor VIII replacement was stopped. Liver transplantation can be considered as definitive therapy for haemophilia.

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Source
http://dx.doi.org/10.1016/s0750-7658(01)00423-3DOI Listing

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