[Enhancement of efficacy of neoadjuvant polychemotherapy in combined treatment of lung cancer].

It is not infrequently that the known preoperative chemotherapy options come to be not very effective in the treatment of patients with pulmonary cancer by reason of a fraction of chemoresistant tumour cells. To enhance effectiveness of treatment we attempted preoperative thermochemotherapy. As many as 62 patients with pulmonary cancer were exposed preoperatively to a 40-minute r. f. hyperthermia plus chemotherapy. All these underwent radical surgery. The above method of neoadjuvant treatment permitted increasing significantly the 3-year survival of those patients presenting with locally spread pulmonary cancer.