[Comparative evaluation of clinical, cytological and cell culture methods of candida vulvovaginitis diagnosis].

Arkh Patol

St-Petersburg Medical Academy of Postgraduate Education, 193015, St-Petersburg.

Published: September 2001

AI Article Synopsis

  • The study involved 98 patients with Candida vulvovaginitis (CVV), classifying them into three clinical forms: acute (26 patients), subacute (23 patients), and remission (49 patients).
  • The clinical diagnosis was confirmed in 87.7% of cases through cytology or culture before treatment, and 4% cytologically in remission, with 20 patients showing positive cultures.
  • The findings indicated that in acute CVV, Candida mainly presented in the budding phase (84.4%), while the cytological method proved to be more cost-effective and efficient compared to cultural methods.

Article Abstract

98 patients with Candida vulvovaginitis (CVV) were examined clinically, cytologically and culturally. Three clinical forms of CVV were distinguished: acute and subacute (26 and 23 patients, respectively)--before treatment, and remission (49 patients)--after treatment. The clinical diagnosis of CVV before the treatment was confirmed cytologically and/or in cultures (87.7%), in remission cytologically (4%), by cultures (20 patients). Candida in the phase of budding and pseudomycelium were prevalent in acute CVV (84.4%). In a subacute form Candida occurred in 30.3%, while in the remaining cases blastospores were observed. Significant correlation between the intensity of Candida colonies growth and phase of development on the mucous membrane was not found. Compared to the cultural method, the cytological technique is more cost effective, faster and simpler.

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