A comparison of the clinical and radiographic results of patients with metal-backed monoblock Insall-Burstein I and modular Insall-Burstein II Posterior Stabilized Knee Prostheses was done. The minimum followup was 10 years. The clinical results were comparable with a similar average Hospital for Special Surgery knee score of 85 and 84 points, respectively. Likewise, the Knee Society Knee and Functional Scores showed no statistical difference. Radiographically, the incidence of minor radiolucent lines was 11% for the Insall-Burstein I prostheses and 29% for the Insall-Burstein II prostheses, but their presence was of no clinical significance. There was no clinical or radiographic evidence of tibial component loosening with either prosthetic design and there were no revisions for polyethylene wear or osteolysis in either cohort of patients.
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J Orthop Surg Res
January 2025
Department of Orthopaedic and Trauma Surgery, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany.
Background: Osteoporosis, a skeletal disorder affecting nearly 20% of the global population, poses a significant health concern, with osteoporotic vertebral body fractures (VBF) representing a common clinical manifestation. The impact of osteoporotic sintering fractures in the thoracolumbar spine on the sagittal lumbar profile is incompletely understood and may lead to the onset of clinical symptoms in previously asymptomatic patients.
Methods: This retrospective single-center study analyzed data from patients presenting with osteoporotic spine fractures between 2017 and 2022.
NPJ Precis Oncol
January 2025
Clinical Pharmacology and Quantitative Science, Genmab Inc, Princeton, NJ, USA.
Tumor genomic profiling is often limited to one or two timepoints due to the invasiveness of tissue biopsies, but longitudinal profiling may provide deeper clinical insights. Using ctDNA data from IMpower150 study, we examined genetic changes in metastatic non-squamous NSCLC post-first-line immunotherapy. Mutations were most frequently detected in TP53, KRAS, SPTA1, FAT3, and LRP1B at baseline and during treatment.
View Article and Find Full Text PDFSci Rep
January 2025
Divisions of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN, 55455, USA.
OrthoFusion, an intuitive super-resolution algorithm, is presented in this study to enhance the spatial resolution of clinical CT volumes. The efficacy of OrthoFusion is evaluated, relative to high-resolution CT volumes (ground truth), by assessing image volume and derived bone morphological similarity, as well as its performance in specific applications in 2D-3D registration tasks. Results demonstrate that OrthoFusion significantly reduced segmentation time, while improving structural similarity of bone images and relative accuracy of derived bone model geometries.
View Article and Find Full Text PDFEur J Trauma Emerg Surg
January 2025
Department of Orthopaedics, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Purpose: (1) To evaluate the incidence and combination types of concomitant malleolar and fibular fractures in patients with distal spiral tibial shaft fractures. (2) To evaluate the risk factors for concomitant malleolar fractures in patients with distal spiral tibial shaft fractures.
Methods: A retrospective review was performed on 64 cases of surgically treated distal spiral tibial shaft fractures with complete radiographs and computed tomography (CT) scans.
Radiography (Lond)
January 2025
UniSA Allied Health & Human Performance, University of South Australia, Adelaide, SA 5001, Australia.
Introduction: Radiographers support the multidisciplinary team by facilitating medical imaging within the operating theatre environment. This project aimed to enhance student readiness for clinical competency in operative theatre imaging by implementing an authentic C-arm simulator for students to use prior to attending clinical placement.
Methods: This study followed a pre-post, quantitative study design.
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