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From micro to macro, nanotechnology demystifies acute pancreatitis: a new generation of treatment options emerges.
J Nanobiotechnology
January 2025
Department of Gastroenterology, Shanghai Institute of Pancreatic Diseases, National Key Laboratory of Immunity and Inflammation, Changhai Hospital, Naval Medical University, Shanghai, 200433, China.
Acute pancreatitis (AP) is a disease characterized by an acute inflammatory response in the pancreas. This is caused by the abnormal activation of pancreatic enzymes by a variety of etiologic factors, which results in a localized inflammatory response. The symptoms of this disease include abdominal pain, nausea and vomiting and fever.
View Article and Find Full Text PDFMedical Student Musculoskeletal Knowledge: Examining the Impact and Value of an Orthopaedic Surgery Clerkship Using the Freedman and Bernstein Examination.
BMC Med Educ
January 2025
Department of Orthopaedics and Rehabilitation, Yale School of Medicine, 47 College Street, 2nd Floor, New Haven, CT, 06510, USA.
Purpose: Given the importance of musculoskeletal knowledge but the limited orthopaedic instruction offered in medical school, our Orthopaedic Surgery Department developed a three-week clerkship for interested students. This study assesses the clerkship's impact on medical student musculoskeletal knowledge through administration of the Freedman and Bernstein Basic Cognitive Musculoskeletal Examination.
Methods: Medical students enrolled in the orthopaedic surgery clerkship between February 2019 and May 2024 were asked to participate in pre- and post-clerkship surveys using the Freedman and Bernstein Basic Cognitive Musculoskeletal Examination.
A pre-rule for the sequential probability ratio test in a between-item grid multidimensional computerized classification test.
Behav Res Methods
January 2025
Institute of Learning Sciences and Technologies, National Tsing Hua University, Hsinchu, 300044, Taiwan.
The measurement efficiency of a grid multidimensional computerized classification test (grid MCCT), which makes a classification decision per dimension, can be improved by taking the correlations between the dimensions into account in the termination criterion. The higher the correlations, the better the improvement in measurement efficiency. However, a termination criterion utilizing inter-dimensional information (i.
View Article and Find Full Text PDFThe Role of Gut Microbiota in Shaping Immune Responses in Tephritidae Fruit Fly and Prospective Implications for Management.
Neotrop Entomol
January 2025
State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Key Laboratory of Bio Pesticide and Chemical Biology, MOE, College of Plant Protection, Fujian Agriculture and Forestry Univ, Fuzhou, China.
The interaction of microbial communities with host immunity has become one of the most explored research areas with significant implications for pest control strategies. It has been found that the gut microbiota plays substantial roles in immune response regulation and host-gut microbiome symbiosis, as well as in pathogen resistance and overall fitness in Tephritidae fruit flies that are major pests of agricultural importance. In this review, we discuss the modulation of immune responses of Tephritidae fruit flies by the gut microbiota with particular emphasis on the general interactions between microbiota and the immune system.
View Article and Find Full Text PDFFilipinos and Parkinson's disease: A scoping review of the literature.
Parkinsonism Relat Disord
January 2025
The Queen's Medical Center, 1301 Punchbowl Street, Honolulu, HI 96813, USA; University of Hawai'i at Manoa, John A. Burns School of Medicine, 651 Ilalo Street, Honolulu, HI 96813, USA.
Background: Filipinos are the third largest sub-group of Asian Americans in the United States and have greater socioeconomic and health disparities than many other Asian sub-groups [1,2,3,4,5,6,7,8]. Characteristics of Filipino patients with Parkinson's disease (PD) have not been adequately studied.
Objective: To scope the extent, range and nature of current knowledge on PD in Filipino-American (FA) patients in contrast to Filipino patients in general.
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