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Incisional PSMA PET/CT-positive recurrences in prostate cancer- is there an implication on clinical care?
Clin Exp Metastasis
January 2025
Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Oligorecurrent prostate cancer (PCa) can be treated with metastasis-directed therapy (MDT), which may be performed using radioguided surgery (RGS) as an experimental approach. These procedures have shown promising outcomes, largely due to the high lesion detection rate of positron emission tomography/computed tomography (PET/CT). We present a case series of patients who underwent RGS following robot-assisted radical prostatectomy (RARP).
View Article and Find Full Text PDFThe relationship between C-reactive protein to lymphocyte ratio and the prevalence of chronic kidney disease in US adults: a cross-sectional study.
Front Endocrinol (Lausanne)
January 2025
Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Objective: The C-reactive protein/Lymphocyte Ratio (CLR) is a novel biomarker whose role in the development of chronic kidney disease (CKD) is not well understood. This study aimed to investigate the correlation between CLR and the prevalence of CKD.
Methods: This cross-sectional study included participants from the US National Health and Nutrition Examination Survey conducted between 1999 and 2010.
Development of a multi-laboratory integrated predictive model for silicosis utilizing machine learning: a retrospective case-control study.
Front Public Health
January 2025
Department of Laboratory, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Objective: Due to the high global prevalence of silicosis and the ongoing challenges in its diagnosis, this pilot study aims to screen biomarkers from routine blood parameters and develop a multi-biomarker model for its early detection.
Methods: A case-control study was conducted to screen biomarkers for the diagnosis of silicosis using LASSO regression, SVM and RF. A sample of 612 subjects (half cases and half controls) were randomly divided into training and test groups in a 2:1 ratio.
Association between early dietary patterns and cardiometabolic health at age 8: a confirmatory analysis of the European Childhood Obesity Project.
Nutr J
January 2025
Paediatrics, Nutrition and Development Research Unit, Universitat Rovira i Virgili. Reus, Tarragona, Spain.
Background & Aim: Metabolic and cardiovascular health outcomes are strongly influenced by diet. Dietary habits established in early childhood may persist into adulthood. This study aimed to examine the association between dietary patterns at both 2 and 8 years of age, explaining the maximum variability of high- and low-quality fats, sugars, and fibre, and cardiometabolic markers at age 8 years.
View Article and Find Full Text PDFImpact of polyvinyl chloride nano-plastics on the biochemical status of Oreochromis niloticus under a predicted global warming scenario.
Sci Rep
January 2025
Department of Zoology, Faculty of Science, Cairo University, Giza, Egypt.
Plastic pollution and global warming are widespread issues that lead to several impacts on aquatic organisms. Despite harmful studies on both subjects, there are few studies on how temperature increases plastics' adverse effects on aquatic animals, mainly freshwater species. So, this study aims to clarify the potential impact of temperature increases on the toxicological properties of polyvinyl chloride nano-plastics (PVC-NPs) in Nile tilapia (Oreochromis niloticus) by measuring biochemical and oxidative biomarkers.
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