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Recruitment, follow-up and survival in an 11-country cohort study of patients at the end of life and their relatives.
PLoS One
January 2025
Institute for Palliative Care, Region Skåne and Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Background: Large, international cohort studies generate high-level evidence, but are resource intense. In end-of-life care such studies are scarce. Hence, planning for future studies in terms of data on screening, recruitment, retention and survival remains a challenge.
View Article and Find Full Text PDFA matter of complexity? The role of the dorsal posterior parietal cortex in processing changes in spatial information across time.
Behav Neurosci
January 2025
Department of Psychology and Program in Neuroscience, Providence College.
The posterior parietal cortex (PPC) is an associative neocortical region that integrates multiple streams of information and is implicated in spatial cognition and decision making. In some cases, however, the PPC is not required for these functions. One possibility is that the PPC is recruited when spatial complexity is high.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Background: The 18F-AV-1451 radioligand enables in-vivo identification of tau neurofibrillary tangles that are considered as biomarkers of neurodegeneration in Alzheimer Disease (AD). However, off-target radioligand binding is also observed in basal ganglia, known as an iron-rich region. Hence, it is important to distinguish between radioligand-identified tissue neurodegeneration and iron-related radioligand binding effects.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Background: The burden of Alzheimer's disease and related dementias is growing fast in Africa. The Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the Alzheimer's Disease Sequencing Project (READD-ADSP) has commenced recruitment of 5000 African participants (AD and cognitively unimpaired individuals) to generate genomic and biomarker data to better characterize AD genetic architecture in Africa. Participating countries, part of the African Dementia Consortium (AfDC) include Nigeria, Ghana, Benin, Cameroon, Uganda, Kenya, Ethiopia, Tanzania, and Mozambique.
View Article and Find Full Text PDFPublic Health.
Alzheimers Dement
December 2024
Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA.
Background: To be successful, recruitment registries must retain participants until they can be recruited to studies. Yet, strategies and tactics to improve retention in online recruitment registries remain understudied. This study seeks to quantify the preferences of registry participants' when it comes to video message content aimed at increasing registry renewal.
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