Using 255 serum samples with various reactivities, we evaluated the Syphilis Fast latex agglutination test (Syphilis Fast) against the Treponema pallidum particle agglutination test (TP-PA) for confirming a diagnosis of syphilis. We found 98.8% agreement between the Syphilis Fast and the TP-PA. The Syphilis Fast, however, had a couple of advantages over the TP-PA: the test takes only 8 min to perform and produces results that are easy to read. It appears to be a good confirmatory test for syphilis, especially for point-of-care clinics such as prenatal or sexually transmitted disease clinics.
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http://dx.doi.org/10.1128/CDLI.8.4.841-842.2001 | DOI Listing |
JAMIA Open
February 2025
Georgia Tech Research Institute, Atlanta, GA 30308, United States.
Objective: The resurgence of syphilis in the United States presents a significant public health challenge. Much of the information needed for syphilis surveillance resides in electronic health records (EHRs). In this manuscript, we describe a surveillance platform for automating the extraction of EHR data, known as SmartChart Suite, and the results from a pilot.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
School of Medical Technology, Xinxiang Medical University, Xinxiang 453003, China; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430207, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
Syphilis (T. pallidum) is a systemic and sexually transmitted disease. Over 80 % of syphilis infections are asymptomatic, and some patients tend to conceal high-risk sex histories.
View Article and Find Full Text PDFOpen Forum Infect Dis
October 2024
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G D'Alessandro, " University of Palermo, Palermo, Italy.
Acta Med Philipp
September 2024
Department of Dermatology, Philippine General Hospital, University of the Philippines Manila.
Nodular syphilis with a granulomatous inflammatory histopathologic pattern is an uncommon cutaneous presentation of secondary syphilis which could pose a diagnostic challenge for clinicians and pathologists alike. A 33-year-old male diagnosed with HIV presented with a 5-week history of asymptomatic generalized erythematous papules and nodules with overlying scales, with involvement of the palms and soles. Histopathologic examination of a nodule from the forearm revealed non-caseating granulomas in a background of a mixed cell inflammatory infiltrate composed of lymphocytes, epithelioid and foamy histiocytes, plasma cells, neutrophils, and multinucleated giant cells.
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