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A Rare Presentation of Disseminated Peritoneal Leiomyomatosis Following Laparoscopic Hysterectomy and Its Multidisciplinary Management.
Cureus
December 2024
Pathology, New Medical Centre Royal Hospital, Khalifa City, Abu Dhabi, ARE.
Disseminated peritoneal leiomyomatosis (DPL) is a rare entity. It is a benign disease but can mimic disseminated malignancy with extensive disease at multiple sites within the abdominopelvic cavity. The primary contributing factor is postulated to be peritoneal spillage of benign leiomyoma, especially after laparoscopic intervention, although hormonal influences might also play a role.
View Article and Find Full Text PDFRisk Stratification of Uterine Smooth Muscle Tumors: The Role of Morphology, Immunohistochemistry, and Molecular Testing.
Adv Anat Pathol
January 2025
Department of Pathology, University of Michigan-Michigan Medicine, Ann Arbor, MI.
Uterine smooth muscle neoplasms are a biologically and clinically heterogeneous group of tumors. Morphology is the cornerstone of pathologic diagnosis of these tumors, and most are readily classified as benign or malignant on the basis of routine histologic examination. However, rare subsets-including intravenous leiomyomatosis, benign metastasizing leiomyoma, and disseminated peritoneal leiomyomatosis-have a capacity for extrauterine spread despite benign cytomorphology.
View Article and Find Full Text PDF3D Imaging Reconstruction and Laparoscopic Robotic Surgery Approach to Disseminated Peritoneal Leiomyomatosis.
J Minim Invasive Gynecol
October 2024
Department of Public Health (Drs. Sardo, Giampaolino, and Bifulco), University of Naples Federico II, Naples, Italy.
Article Synopsis
- * The innovative combination was aimed at improving surgical outcomes by providing better identification of myomas, reducing operation times, and minimizing blood loss during the surgery.
- * The intervention successfully resulted in the removal of 15 myomas with a total operative time of 120 minutes and low blood loss, showcasing the effectiveness of this advanced surgical approach.
Disseminated peritoneal leiomyomatosis: A benign condition with diagnostic and therapeutic challenges.
Qatar Med J
September 2024
Obstetrics and Gynaecology Department, Federal Medical Centre Keffi, Keffi, Nigeria.
Article Synopsis
- Disseminated peritoneal leiomyomatosis (DPL) is characterized by multiple abdominal nodules that are similar to uterine fibroids and often pose diagnostic and treatment challenges.
- A 25-year-old woman with a history of myomectomy presented with recurrent lesions, leading to multiple surgeries, including a total abdominal hysterectomy and hormonal therapy with letrozole.
- Effective management of DPL is complex, requiring individualized approaches based on patient age, fertility desires, and the number of lesions, as it tends to recur frequently.
A Rare Case of Disseminated Peritoneal Leiomyomatosis: A Case Report.
Indian J Radiol Imaging
October 2024
Department of Radiodiagnosis, St John's Medical College and Hospital, Bangalore, Karnataka, India.
Disseminated peritoneal leiomyomatosis is a benign condition characterized by multiple extrauterine leiomyomas in various locations such as the peritoneum, mesentery, abdominal wall, and pelvis. This is typically observed following laparoscopic myomectomy and is an extremely rare disease, with only a limited number of cases reported thus far. It primarily affects women in their reproductive age group and is believed to be associated with ovarian secretions.
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