Physical training produces definite changes in the state of the blood and renal kininine system. In skilled sportsmen the renal kinine system has a higher resistance to the effect of an intensive muscular work than that in physically untrained individuals. At rest the level of the kinine system enzymes in the blood of sportsmen is lower than in untrained persons. On effort sportsmen demonstrate a moderate, but protractedly rising kininogenesis. The functional potentialities of the renal kinine system in sportsmen th hypertensive disease of the I degree continue to be higher than they are in untrained patients. The development of an adequate reaction of the renal and blood kininine system under different conditions appears as one of the mechanisms of the prophylactic effect produced by physical training in hypertensive disease.

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