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Antioxidant activities of three enzymatic hydrolysates from on HaCaT cells and zebrafish .
Nat Prod Res
January 2025
Department of School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, China.
To explore the antioxidant activity of enzymatic hydrolysates of from Dalian and preliminarily elucidate their mechanisms of action both and . Samples were hydrolysed using alcalase, protamex, and neutrase. 2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl (DPPH) and 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical scavenging assays showed that the alcalase hydrolysate had the highest antioxidant activity, with IC values of 4.
View Article and Find Full Text PDFUltrasonic/microwave-assisted extraction and properties of polysaccharides from .
Prep Biochem Biotechnol
January 2025
Xinjiang University, Xinjiang, China.
This study aimed to optimize the ultrasonic/microwave-assisted extraction (UAME) technique of polysaccharides (EAP-UM) by response surface methodology (RSM). The optimum conditions include: solid-liquid ratio of 1:23 g/mL, ultrasonic power of 252 W, microwave power of 417 W, and extraction time of 11 min. Under these conditions, the yield of polysaccharides reached 7.
View Article and Find Full Text PDFComparison of Antioxidant Activities of Extracts According to Harvest Area.
Rejuvenation Res
January 2025
Department of Integrative Biosciences, University of Brain Education, Cheonan, Republic of Korea.
is a medicinal plant native to East Asia with its diverse therapeutic potentials. In particular, the antioxidant effect of this plant is well known, but there has been little research on the antioxidant effect according to different habitats or ages. In this study, we evaluated the proximate composition, mineral, saponin, rutin, total phenolic and flavonoid contents, and antioxidant activities of leaf extracts of plants cultivated from two different regions (New Zealand and Jeju Island, Korea) and of the same age (2-year-old plants).
View Article and Find Full Text PDFFerroptosis- and stemness inhibition-mediated therapeutic potency of ferrous oxide nanoparticles-diethyldithiocarbamate using a co-spheroid 3D model of pancreatic cancer.
J Gastroenterol
January 2025
Division of Surgical Oncology, Department of Surgery, University of Alabama at Birmingham (UAB), Birmingham, Alabama, 35294, USA.
Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a high mortality rate and exhibits a limited response to apoptosis-dependent chemotherapeutic drugs (e.g., gemcitabine, Gem).
View Article and Find Full Text PDFPomegranate as a natural remedy for gastric ulcers prevention: a review of its gastroprotective mechanisms and pharmacological benefits.
Naunyn Schmiedebergs Arch Pharmacol
January 2025
School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, 1988873554, Iran.
Gastric ulcers (GUs) represent a common gastrointestinal disorder characterized by mucosal damage and inflammation, often precipitated by factors such as Helicobacter pylori infection and the consumption of COX inhibitors. This comprehensive review investigates the role of oxidative stress and inflammation in the pathogenesis of GUs and assesses the potential therapeutic effects of Punica granatum (pomegranate, Pg) supplementation. Utilizing a series of experimental models, including indomethacin, aspirin, and alcohol-induced ulcers, we demonstrate that Pg extracts possess significant gastroprotective properties.
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