Time resolved measurements of the growth of Raman instabilities were performed using a picosecond chirped laser pulse. It was observed experimentally that for a short laser pulse (<10 ps), forward and 30 degrees Raman scattering occur at the back of the pulse. The growth of the instabilities was found to be independent of the sign of the chirp. In addition, a simple temporal model was developed and shows good agreement with the experimental results. This model also indicates that the plasma wave driven by forward Raman scattering is severely damped in the case of pulses longer than a few picoseconds. Damping by the modulational instability is compatible with the experimental results.
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http://dx.doi.org/10.1103/PhysRevE.63.065401 | DOI Listing |
Transverse mode instability (TMI) significantly limits the power scaling of ytterbium-doped fiber lasers. In this Letter, what we believe to be a novel TMI mitigation strategy is proposed and demonstrated in a bidirectional output fiber laser. On the basis of the continuous wave (CW) pump, integrating a quasi-continuous wave (QCW) pump can effectively improve the TMI threshold of the system.
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November 2024
State Key Laboratory of Digital Medical Engineering, School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 210096, China; State Key Laboratory of Digital Medical Engineering, School of Electronic Science and Engineering, Southeast University, Nanjing, 211189, China. Electronic address:
Surface-enhanced Raman scattering (SERS) shows great promise for early diagnosis due to its high specificity and rapid detection capabilities. However, its application is often hindered by substrate instability and insufficient interaction between the substrate and incident light. To address these challenges, a photonic-plasmonic strategy is often employed to enhance sensing performance but it is generally limited by the low efficiency of plasmonic metal and optical cavity resonances.
View Article and Find Full Text PDFBiosens Bioelectron
February 2025
Keenan Research Center for Biomedical Science, Unity Health Toronto, Toronto, Ontario, M5B 1W8, Canada; Institute for Biomedical Engineering, Science and Technology (iBEST), Partnership Between Toronto Metropolitan University (formerly Ryerson University) and St. Michael's Hospital, Toronto, ON, M5B 1W8, Canada; Nano Characterization Laboratory, Faculty of Engineering and Architectural Sciences, Toronto Metropolitan University (formerly Ryerson University), 350 Victoria Street, Toronto, ON, M5B 2K3, Canada; Nano-Bio Interface Facility, Faculty of Engineering and Architectural Sciences, Toronto Metropolitan University (formerly Ryerson University), 350 Victoria Street, Toronto, ON, M5B 2K3, Canada. Electronic address:
J Pharm Biomed Anal
February 2025
Department of Pharmacy, University of Patras, Rio, Achaias GR-26504, Greece. Electronic address:
Any polymorphic conversion of an active pharmaceutical ingredient (API), even if partial, is likely to lead to changes in its efficiency and safety. Posaconazole, an antifungal drug, is detected as Form-S in the commercially available oral suspensions. However, a mixture of Form-S and the initial Form I is likely to coexist depending either on the manufacturing process of the suspensions and/or to the storage conditions of the suspension.
View Article and Find Full Text PDFPhys Rev E
October 2024
Department of Mechanical Engineering, University of Rochester, Rochester, New York 14627, USA.
Laser-plasma instabilities under ignition conditions for direct-drive inertial confinement fusion are studied using two-dimensional particle-in-cell simulations with a combination of in-plane (PP) and out-of-the-plane (SP) lasers. The results show that stimulated Raman side-scattering can induce significant pump depletion and form a gap in the Raman scattered-light spectra that have been observed in experiments.
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