[Primary malignant melanoma of the cervix uteri: apropos of 1 case with review of the literature].

Gynecol Obstet Fertil

Laboratoire d'anatomie pathologique, CHU Ibn Rochd, quartier des hôpitaux, Casablanca, Maroc.

Published: May 2001

The authors report a case of malignant melanoma of the cervix uteri diagnosed in a young 35-year-old patient. Isolated genital bleeding was the beginning symptom. The physical exam showed a cervical dark tumor, with extension into the vagina (superior third), the parametrium was free. Cervical biopsy concluded to a malignant melanoma. No other abnormalities were observed and the tumor was classed stage IIA-FIGO. A total hysterectomy with bilateral annexectomy and pelvic lymphadenectomy was performed. In the way, the patient died after ten months by local and general recurrence. Primitive malignant melanoma of the cervix uteri is rare. Only 39 cases are reported in literature at this day. It is usually initially misdiagnosed mainly in the achromic forms, then the immuno-histochemical study is useful. Its treatment is not well codified and its histogenesis was controversial for a long time.

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http://dx.doi.org/10.1016/s1297-9589(01)00148-5DOI Listing

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