A 34-year-old man presented with recent severe headache. Neurological examination found gait disturbance and a static cerebellar syndrome. The CT scan showed a tumor located in the fourth ventricle and which presented with a density close to that of the cerebellar parenchyma, without contrast enhancement, associated with an enlargement of the third and the lateral ventricles. MRI showed that the tumor had an heterogeneous hyposignal on T1-weighted images and an hypersignal on T2-weighted images, without associated edema; the roof of the fourth ventricle was displaced upward and the brain stem forward. At operation, an encapsulated epidermal cyst, developed from the cerebellar vermis, without attachment to the floor of the fourth ventricle, was totally removed. Epidermal cysts of the fourth ventricle are unusual lesions; their capsule often adhere to the floor and cannot be totally removed. Those developed from the cerebellar vermis seem to be rarer. With the use of MRI, their true origin could be suspected. In these cases, the cysts can be totally removed, reducing the risk of recurrence
Download full-text PDF |
Source |
---|
Introduction Pediatric hemifacial spasm (HFS) is rare, presenting early in infancy, and often fraught with subsequent psychomotor and intellectual deficits. Fourth ventricular hamartoma (FVH) is a rare cause of HFS with only 5 cases reported in literature. While Gamma-knife radiosurgery (GKRS) has been used to treat hypothalamic hamartomas, this is the first case of FVH treated with primary GKRS.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Background: Cerebrospinal fluid (CSF) dynamics are increasingly studied to understand potential pathologic coupling with neurological disorders. In Alzheimer's disease (AD), CSF dynamics may be altered secondary to AD-related atrophy and enlarged CSF spaces. Additionally, animal studies suggest that altered CSF dynamics could impair clearance of metabolic waste, leading to accumulation of amyloid-beta (Aβ).
View Article and Find Full Text PDFAlzheimers Dement
December 2024
School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Background: Cerebrospinal fluid (CSF) dynamics are increasingly studied to understand potential pathologic coupling with neurological disorders. In Alzheimer's disease (AD), CSF dynamics may be altered secondary to AD-related atrophy and enlarged CSF spaces. Additionally, animal studies suggest that altered CSF dynamics could impair clearance of metabolic waste, leading to accumulation of amyloid-beta (Aß).
View Article and Find Full Text PDFObjective: Ependymomas, rare neuroglial tumors originating from ependymal cells, can occur in the CNS and typically affect the brain's ventricles or spinal cord. Prognosis is influenced by tumor grade, location, resection extent, and preoperative Karnofsky Performance Status Scale (KPSS) scores. This study evaluates clinical features, treatment outcomes, and factors affecting prognosis in patients with intracranial ependymomas.
View Article and Find Full Text PDFFront Oncol
December 2024
Head and Neck Oncology Ward, West China Hospital of Sichuan University, Chengdu, China.
Background: Histiocytic sarcoma originates in various tissues, including the skin, lymph nodes, gastrointestinal tract, lungs, bone marrow, and central nervous system. Primary central nervous system histiocytic sarcoma (PCNSHS) is exceptionally rare, known for its aggressive behavior and poor prognosis. This report describes a case of PCNSHS in the cerebellum treated with surgery and radiotherapy.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!