AI Article Synopsis
- Recent literature indicates that oncogenic heterotrimeric G-proteins play a significant role in the development of tumors in endocrine tissues.
- The gsp-oncogene, responsible for coding stimulatory G-proteins, is identified as a key factor in the formation of certain pituitary and thyroid tumors.
- Despite this finding, the impact of other oncogenic G-proteins on tumor formation is still not well understood.
Article Abstract
New data available in the literature on the role of oncogenic heterotrimeric GTP-proteins (G-proteins) in endocrine tissue carcinogenesis have been analyzed. A conclusion is made that stimulatory G-proteins coded by the gsp-oncogene are a major factor of the development of some pituitary and thyroid tumors. However, the role of the other oncogenic G-proteins in tumorigenesis remains unclear.
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