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Standardized Mortality Ratios (SMRs) and Radon Exposure Analysis for Lung Cancer and All-Cause Mortality in Locorotondo, Southern Italy.
Medicina (Kaunas)
December 2024
Interdisciplinary Department of Medicine, University of Bari, Piazza G. Cesare, 11, 70124 Bari, Italy.
: Radon is a known risk factor for lung cancer, and residential radon exposure is the leading cause of lung cancer in never smokers; however, in Italy, there is still a lack of public awareness regarding the risk caused by residential radon exposure. In this mortality study, which was carried out in an Italian Apulian town (Locorotondo) of the Bari province, we aimed to analyze lung cancer mortality and all-cause mortality in a population highly exposed to radon. : The study period was 1998-2021.
View Article and Find Full Text PDFFrom collective to individual radon risk exposure: An insight into the current European regulation.
Environ Int
January 2025
Dipartimento di Geoscienze, Università di Padova, Padova, Italy.
Radon (Rn) is a radioactive gas with well-documented harmful effects; the World Health Organization has confirmed it as a cancerogenic for humans. These detrimental effects have prompted Europe to establish national reference levels to protect the exposed population. This is reflected in European directive 59/2013/EURATOM, which has been transposed into the national regulations of EU Member States.
View Article and Find Full Text PDFExhalation of Rn-219 by patients treated with Radium-223.
EJNMMI Phys
January 2025
Department for Radiation Protection and Medical Physics, Hannover Medical School, Carl-Neuberg- Str. 1, 30625, Hannover, Germany.
Background: Treatment with Ra-223 dichloride is approved for the therapy of castration resistant prostate cancer (CRPC) with symptomatic bone metastases and no known visceral metastases in Europe since 2013, and Ra-223 is under discussion for labelling other molecules and nanoparticles. The direct progeny of Ra-223 is Rn-219, also known as actinon, a radioactive noble gas with a half-life of 3.98 s.
View Article and Find Full Text PDFAn activity concentration-based proposal for radon management in workplaces involving NORM in Canada.
Radiat Environ Biophys
December 2024
Radiation Protection Bureau, Health Canada, 775 Brookfield Road, Ottawa, ON, K1A 1C1, Canada.
The Canadian Guidelines for the Management of Naturally Occurring Radioactive Materials (NORM) have been developed to manage radiation doses received in workplaces involving NORM, such as mineral extraction and processing, oil and gas production, metal recycling or water treatment facilities. This management strategy works well for most naturally occurring radioactive materials in workplaces, with the exception of radon. Radon is a naturally occurring radioactive gas generated by the decay of uranium-bearing minerals in rocks and soils.
View Article and Find Full Text PDFThe role of exosomal hsa-miR-125b-5p and hsa-miR-320c as non-invasive biomarkers in high-radon areas of Kazakhstan.
Biomarkers
January 2025
Department of General Biology and Genomics, Institute of Cell Biology and Biotechnology, L.N. Gumilyov Eurasian National University, Astana 010008, Kazakhstan.
Background: Radon, a radioactive gas, is a significant risk factor for lung cancer, especially in non-smokers. This study examines the expression of exosomal microRNAs (miRNAs) as potential biomarkers for radon-induced effects.
Methods: A total of 109 participants from high- and low-radon areas in Kazakhstan were included.
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