Information from different regions of the visual field travels through specific bundles of retinal ganglion cell axons. This visual information is disrupted in patients with glaucoma, and the effects can be seen in measurements of the visual field and optic nerve. Typical shapes and sizes of glaucomatous field defects result from damage to these nerve fiber bundles at the level of the optic disk, and we have identified specific patterns of progression. These patterns apply to the visual function-specific field tests that are designed to indirectly assess sub-populations of retinal ganglion cells. The rationale for these tests is described. An argument for the importance of using visual function techniques to assess progression in an individual patient is given.
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http://dx.doi.org/10.1016/s0039-6257(01)00196-5 | DOI Listing |
MethodsX
June 2025
Department of Computer Science and Engineering, Vel Tech Rangarajan Dr.Sagunthala R&D Institute of Science and Technology, Tamil Nadu 600062, India.
The disease affects the optic nerve and represents the principle reasons of irreversible vision loss, mostly asymptomatic and uncontrolled. Consequently, early and accurate diagnosis is critical to prevent or reduce its effect, however, conventional diagnostic techniques often fail to provide concrete results. In this regard, we present a new approach built on Generative Adversarial Networks (GAN) and MobileNetV2 pretrained architecture for diagnosing glaucoma.
View Article and Find Full Text PDFGMS Ophthalmol Cases
December 2024
Universidade Federal do Paraná (UFPR), Curitiba, Brazil.
Purpose: Idiopathic elevated episcleral venous pressure (IEEVP) or Radius-Maumenee syndrome (RMS) is a rare disease without any identified underlying cause. An increasing episcleral venous pressure (EVP) leads to raised intraocular pressure (IOP) and consequently glaucomatous damage of the optic nerve. The objective of this paper is to report this rare condition as well as its clinical management.
View Article and Find Full Text PDFAm J Ophthalmol Case Rep
March 2025
Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, NY, USA.
Purpose: We present a case of Kikuchi-Fujimoto Disease (KFD) associated with bilateral optic neuropathy progressing to vision loss.
Observations: A 17-year-old male was referred for bilateral optic nerve pallor. Eight years prior, he was diagnosed with KFD after workup for lymphadenopathy and treated with prednisolone acutely followed by long-term Plaquenil.
Neurosurg Rev
January 2025
Department of Surgery, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Objective: Increased intracranial pressure (ICP) can worsen the clinical condition of traumatic brain injury (TBI) patients. One non-invasive and easily bedside-performed technique to estimate ICP is ultrasonographic measurement of optic nerve sheath diameter (ONSD). This study aimed to analyze ONSD and correlate it with ICP values obtained by intraparenchymal monitoring to establish the ONSD threshold value for elevated ICP and reference range of ONSD in severe TBI patients.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia; Department of Pathology and Laboratory Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia. Electronic address:
Introduction: Retinal capillary hemangioma (RCH) is a benign vascular hamartoma that can occur sporadically or as a manifestation of Von Hippel-Lindau (VHL) disease. If left untreated, it results in adverse ocular complications depending on its location and eventual visual loss.
Case Presentation: We present a 50-year-old man who was a known case of VHL with history of left eye vision loss in the left eye at the age of 30 years.
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