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Towards circularity for agro-waste: Minimal soil hazards of olive pomace bioconverted frass by insect larvae as an organic fertilizer.
J Environ Manage
January 2025
CESAM - Centre for Environmental and Marine Studies, Department of Biology, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.
As global populations escalate and the demand for food and feed intensifies, the generation of agri-food waste is becoming an increasingly critical issue. Addressing this challenge is crucial for optimizing food production and advancing sustainable waste management practices. In this context, insects, including the Black Soldier Fly (BSF, Hermetia illucens), present opportunities for circularity through the bioconversion of organic waste.
View Article and Find Full Text PDFOdyssey of environmental and microbial interventions in maize crop improvement.
Front Plant Sci
January 2025
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
Maize () is India's third-largest grain crop, serving as a primary food source for at least 30% of the population and sustaining 900 million impoverished people globally. The growing human population has led to an increasing demand for maize grains. However, maize cultivation faces significant challenges due to a variety of environmental factors, including both biotic and abiotic stresses.
View Article and Find Full Text PDFTamuzimod in patients with moderately-to-severely active ulcerative colitis: a multicentre, double-blind, randomised, placebo-controlled, phase 2 induction trial.
Lancet Gastroenterol Hepatol
January 2025
Department of Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and University Vita-Salute San Raffaele, Milan, Italy.
Background: Tamuzimod (VTX002) is a selective sphingosine 1-phosphate receptor 1 modulator in development for ulcerative colitis. We aimed to assess the safety and efficacy of tamuzimod in patients with moderately-to-severely active ulcerative colitis.
Methods: This double-blind, randomised, placebo-controlled, phase 2 induction trial was conducted at 122 centres across 15 countries in Asia, Europe, and North America.
PCSK9 Inhibitors: Focus on Evolocumab and Its Impact on Atherosclerosis Progression.
Pharmaceuticals (Basel)
November 2024
Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
This paper investigates the therapeutic use of PCSK9 inhibitors, particularly Evolocumab, as monoclonal antibodies for the treatment of atherosclerosis based on recent literature reviews. PCSK9 is an outstanding example of a breakthrough in medical science, with advancements in understanding its biological function driving substantial progress in atherosclerosis treatment. Atherosclerotic cardiovascular disease (ASCVD) is a leading global cause of mortality, imposing substantial financial burdens on healthcare systems.
View Article and Find Full Text PDFA group version of the OurRelationship program within residential substance use treatment: preliminary evidence for improving responses to romantic relationship conflict for those dealing with substance misuse.
Front Psychol
December 2024
Department of Psychology, University of California, Los Angeles, Los Angeles, CA, United States.
The aim of this study was to pilot an adapted version of an online relationships program with residents in treatment for alcohol and other drugs (AOD). The OurRelationship (OR) Program, which is based on Integrative Behavioral Couples Therapy, was piloted in a group-based format to determine whether residents' participation in the program would result in decreases in residents' destructive responses and increases in constructive responses to relationship conflict scenarios as well as reductions in negative affect experienced during these conflict scenarios. Residents ( = 104) across six residential facilities participated in the pilot over 4 weeks.
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