Basic research has allowed the full knowledge of the underlying mechanisms of the use of radiotherapy in cancer treatment. However, in spite of the crop of radiobiological studies, the impact on clinical research in last years has been relatively little. Within the recent research in man, studies on altered dose fractionations, combined radiation and chemotherapy together with the development of sophisticated technology have allowed the use of new methods of radiotherapy while those existing have been optimized.
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Clinicopathological and in Silico Insights into Male Infertility: Agerelated Trends and Anti-sperm Antibodies Post COVID-19 Vaccination.
Curr Med Chem
January 2025
Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Background: Infertility was often considered a female issue, but male infertility emerged significantly after the Covid-19 pandemic. Hence, assessments are crucial for planning policies on health care and family planning and reasons thereof post vaccinations.
Material And Methods: The present study was a case-control, dual-centers, prospective study with normal sperm parameters.
Investigating the Association Between Heavy Metals and Attention Deficit Hyperactivity Disorder in Children: An Exploratory Study.
J Atten Disord
January 2025
Nutrition and Mental Health Research Group (NUTRISAM), Universitat Rovira i Virgili, Tarragona, Spain.
Exposure to heavy metals has been associated with affecting children's neurodevelopment, particularly increasing the risk of developing attention-deficit hyperactivity disorder (ADHD). The current exploratory study aims to investigate potential associations between presence of 15 different heavy metals in urine and ADHD. A total of 190 urine samples of participants from clinical and non-clinical population (non-ADHD = 66; ADHD = 124) aged between 6 and 15 years from Barcelona and Tarragona (Spain) were analysed.
View Article and Find Full Text PDFGender disparities in clinical outcomes of urothelial carcinoma linked to X chromosome gene mutation.
BMJ Oncol
December 2023
NHC Key Laboratory of Glycoconjugate Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
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Methods And Analysis: We enrolled 2438 patients with UC from seven independent real-world cohorts possessing comprehensive clinical and genomic data.
Proceedings of the 1st Symposium "Autoimmune Diseases: Clinical Unmet Needs in Systemic Autoimmune Diseases Guide Clinical, Translational and Basic Research".
Mediterr J Rheumatol
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Pathophysiology Department, Athens School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Lipid Metabolic Heterogeneity during Early Embryogenesis Revealed by Hyper-3D Stimulated Raman Imaging.
Chem Biomed Imaging
January 2025
College of Biomedical Engineering & Instrument Science, Key Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou 310058, China.
Studying embryogenesis is fundamental to understanding developmental biology and reproductive medicine. Its process requires precise spatiotemporal regulations in which lipid metabolism plays a crucial role. However, the spatial dynamics of lipid species at the subcellular level remains obscure due to technical limitations.
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