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Oral Manifestations in Geriatric Patients: An Observational Study in Western Maharashtra.
Cureus
October 2024
Department of Oral Medicine and Radiology, School of Dental Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.
Article Synopsis
- The study investigates oral health issues and their links to systemic diseases among geriatric patients aged 60 and older, conducted at Krishna Vishwa Vidyapeeth's Department of Oral Medicine and Radiology over six months from January to June 2024.
- A total of 100 geriatric patients were examined, with data collected on demographics, personal habits, and medical history, revealing that hypertension and tobacco use were significant findings among the group.
- Common oral health problems identified included periodontitis, partial edentulism, dental caries, and soft tissue issues such as gingivitis and oral cancer, emphasizing the need for targeted dental care for elderly patients.
PRF Lysates Modulate Chemokine Expression in Oral Squamous Carcinoma and Healthy Epithelial Cells.
Bioengineering (Basel)
July 2024
Department of Oral Biology, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
Platelet-rich fibrin (PRF), originally used to support soft tissue healing, is also considered a therapeutic option for treating oral lichen planus and leukoplakia. The progression from the two premalignant lesions to the aggressive malignant oral squamous cell carcinoma involves an inflammatory process linked to chemokine expression. Thus, there is a rationale for studying how PRF modulates the expression of chemokines in oral squamous carcinoma cells.
View Article and Find Full Text PDFTemporalis Flap for Soft Palate Reconstruction - More than an Alternative for Patients Unsuitable for Microvascular Reconstructive Surgery.
In Vivo
March 2024
Department of Oral and Maxillofacial Surgery, Army Hospital Hamburg, Hamburg, Germany.
Background/aim: The treatment of squamous cell carcinoma (SCC) in the oral cavity for operable patients usually consists of surgical tumor resection, unilateral or bilateral neck dissection and defect reconstruction. In addition to local flaps, multiple, particularly microsurgical, distant flaps have been developed, which are mainly considered state of the art reconstruction. However, depending on previous operations and individual patient factors, microsurgical reconstruction is sometimes not suitable.
View Article and Find Full Text PDFEtiology of Oral Potentially Malignant Disorders and Squamous Cell Carcinoma Based on Cellular Stress Regulation and Matrix Stiffness.
Front Biosci (Landmark Ed)
October 2023
Department of Dentistry and Oral Surgery, Keio University School of Medicine, 160-8582 Tokyo, Japan.
Article Synopsis
- The oral cavity is the first part of the digestive system, aiding in food breakdown and interacting with various environmental factors, including microbiota.
- Oral cancer involves abnormal cell behaviors caused by complex interactions between environmental influences and genetic predispositions, complicating treatment and understanding.
- Oral potentially malignant disorders, like leukoplakia and submucous fibrosis, have high cancer risk and may be influenced by mechanical stressors, such as chewing betel quid, affecting tissue stiffness.
A bird's-eye view of pathologist over diagnostic confusion of oral cavity lesions.
J Oral Maxillofac Pathol
July 2023
Department of Pathology, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, India.
Introduction: Oral cavity can be host to multitude of neoplastic, premalignant or non neoplastic pathological lesions. Diagnosis of lesions of oral cavity is always of interest to clinician and pathologist and rely on clinical appearance of lesions. There can be variation in diagnosis of clinical lesion with histopathology.
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