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Emerging trends in cervical cancer incidence among younger Taiwanese generations: an urban-rural comparison.
Ann Med
December 2025
College of Public Health, Institute of Health Data Analytics and Statistics, National Taiwan University, Taipei, Taiwan.
Background: Despite global declines in cervical cancer incidence, certain regions observe unexpected rising trends among younger generations.
Methods: This study uses the age-period-cohort model to examine long-term incidence trends of invasive cervical cancer in Taiwan. Data were sourced from the Taiwan Cancer Registry.
Comparative efficacy of single-coil versus dual-coil ICD leads: a meta-analysis of clinical outcomes.
Future Cardiol
January 2025
Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Background: Implantable cardioverter-defibrillators (ICDs) are essential for reducing sudden cardiac death in patients at risk of ventricular arrhythmias. The choice of ICD lead - single-coil or dual-coil - can influence device performance and patient outcomes. This meta-analysis evaluates the comparative efficacy and safety of single-coil versus dual-coil ICD leads to inform clinical decision-making.
View Article and Find Full Text PDFUpregulation of HSP90α in the lungs and circulation in sarcoidosis.
Front Med (Lausanne)
January 2025
Department of Medicine, Firestone Institute for Respiratory Health, McMaster University, Hamilton, ON, Canada.
Background: Sarcoidosis is a systemic granulomatous disease of unknown cause. Natural improvement with favorable outcome is common, but a significant number of patients present with difficult to manage and progressive disease. The identification of biomarkers associated with disease activity and progression is warranted.
View Article and Find Full Text PDFEffect of adenosine triphosphate on methylphenidate-induced oxidative and inflammatory kidney damage in rats.
Drug Chem Toxicol
January 2025
Department of Pharmacology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan, Türkiye.
The purpose of this trial was to assess the effects of methylphenidate on the kidney tissues and to investigate the protective effect of adenosine triphosphate (ATP) against possible methylphenidate nephrotoxicity in rats. The rats were separated into; healthy control (HG), methylphenidate (MPHG), ATP (ATPG), and ATP+ methylphenidate (AMPG). The ATPG and AMPG groups were administered ATP 4 mg/kg bw/d, and the HG and MPHG groups received distilled water intraperitoneally.
View Article and Find Full Text PDFA systematic review of the cost-effectiveness of anti-VEGF drugs for the treatment of diabetic retinopathy.
Health Technol Assess
January 2025
Centre for Reviews and Dissemination, University of York, York, UK.
Background: Non-proliferative and proliferative diabetic retinopathy are common complications of diabetes and a major cause of sight loss. Anti-vascular endothelial growth factor drugs represent a treatment option for people with diabetic retinopathy and are routinely used to treat various other eye conditions. However, anti-vascular endothelial growth factor drugs are expensive relative to current care options, and it is unclear whether this additional cost is justified when the immediate risk of vision loss is lower compared to patients with more aggressive ophthalmological conditions.
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