To determine if susceptibility testing of Streptococcus pneumoniae could detect those isolates that had one of the recognized mechanisms of fluoroquinolone resistance, 101 isolates were selected; the levofloxacin MIC for 28 of these isolates was > or =4 microg/ml. Only isolates with both parC and gyrA mutations or with no recognized resistance mechanisms were reliably identified by using these results. Isolates with only a parC mutation could not be detected reliably using any susceptibility testing method.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC90572 | PMC |
| http://dx.doi.org/10.1128/AAC.45.6.1911-1914.2001 | DOI Listing |
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