The analysis was performed of aetiological factors and clinical course of sepsis in children admitted to the Institute of Pediatrics of Medical University of Łódź in 1995-1998. Staphyloccocus epidermidis was the most frequently found pathogen in neonates, whereas Neisseria meningitidis in infants and children over 1 year. Candida sp. was responsible for 25% of sepsis in infants. The severity of the disease correlated significantly with increased leucocytosis and shift to the left in the white cell profile as well as elevated levels of bilirubin and transaminases, especially GOT. Lower correlations were found between severity of clinical course and coagulological disturbances or inflammatory changes in the spinal cerebral fluid.
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