Highly regioselective Friedländer reaction.

Org Lett

Department of Process Research, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, USA.

Published: April 2001

[reaction: see text]. A highly regioselective Friedländer reaction is described. By introduction of a phosphonate group at one of the alpha-carbons of a ketone, regioselectivity can be perfectly controlled.

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Source
http://dx.doi.org/10.1021/ol006785vDOI Listing

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