Purpose: To study the occurrence of Parkinson's disease (PD) in the relatives of parkinsonian patients (n=119), and of their matched controls (n=238).Scope: More patients reported a positive family history of PD in their first degree relatives, compared to their controls (OR 2.7, 95% CI 1.3-5.9), and the incidence of PD among those relatives was also significantly higher (OR 1.4, 95% CI 1.1-1.8).Conclusions: Familial occurrence of PD is not necessarily a sign of genetic mechanisms in the etiology of PD. Shared environment with common risk factors might be even more important.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s1353-8020(00)00051-1 | DOI Listing |
Publication Analysis
Top Keywords
familial occurrence
8
occurrence parkinson's
8
parkinson's disease
8
disease community-based
4
community-based case-control
4
case-control study
4
study purpose
4
purpose study
4
study occurrence
4
disease relatives
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!