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Efficient use of penile Doppler ultrasound for investigating men with erectile dysfunction.

J Sex Med

August 2024

Sexual and Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, United States.

Background: Vasculogenic erectile dysfunction is the most common type of erectile dysfunction, and penile Doppler ultrasound (PDUS) is a useful tool to assess erectile hemodynamics in the clinician's effort to discuss prognosis and management strategies with the patient.

Aim: We herein describe the PDUS protocol used at our center, including indications, technique, and data interpretation.

Methods: We describe our institutional experience with PDUS and discuss it in the context of a contemporary review of the literature for this investigation.

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Article Synopsis
  • Priapism is a rare condition that involves a painful, prolonged erection not linked to sexual arousal, with ischemic priapism being the most common type that needs urgent care to avoid lasting damage.
  • The article reviews initial treatment strategies for ischemic priapism, recommending intravascular injections of phenylephrine and aspiration as primary approaches, tailored to individual patient situations.
  • While guidelines provide specific directions for cases lasting over 4 hours, addressing cases of shorter durations poses challenges due to a lack of sufficient evidence.
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This study aimed to investigate the mechanism underlying social stress (SS)-induced erectile dysfunction (ED) and evaluate the effects of a single subanesthetic dose of ketamine on SS-related ED. Male FVB mice were exposed to retired male C57BL/6 mice for 60 min daily over a 4-week period. In the third week, these FVB mice received intraperitoneal injections of either saline (SSS group) or ketamine (SSK group).

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Intracavernosal injection of Trimix (a combination of phentolamine, papaverine, and alprostadil) is used for the treatment of erectile dysfunction. A rare but serious side effect of Trimix is priapism, a persistent erection lasting for more than four hours. Penoscrotal decompression is a newer technique being used to treat refractory and persistent ischemic priapism.

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Objective: To describe two cases of man with the diagnosis of ischemic priapism after the intake of tamsulosin and to revise the scientific literature.

Methods: We present two cases of men that developed an ischemic priapism after the intake of tamsulosin prescribed for STUI and were treated in our hospital. We described the two cases, from the diagnosis until the surgery that was performed.

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