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Fabrication of promising competitive graphene nanocomposite transducer to determine Prucalopride succinate in pharmaceutical formulation and in spiked human biological fluids.
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Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
The development of a newly fabricated ion-selective electrode (ISE) solid-contacted type for the determination of prucalopride succinate represents a significant advancement in analytical chemistry, particularly in the context of green chemistry principles. The optimization process involved numerous trials to ensure the selection of a cation exchanger and ionophore that offer high sensitivity and selectivity for prucalopride succinate. Through these optimization trials, sodium tetrakis was identified as the most suitable cation exchanger, while calix [8] arene demonstrated the highest affinity towards prucalopride succinate as the ionophore.
View Article and Find Full Text PDFAging with HIV: The Burden of Comorbidities, Polypharmacy, and Drug Interactions in Korean People Living with HIV Aged ≥50 Years.
Infect Chemother
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Department of Infectious Diseases, Chonnam National University Hospital, Gwangju, Korea.
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Departments of Internal Medicine and Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, 330 Cedar St, New Haven, CT, 06510, USA.
Background: Overweight and obesity-chronic illnesses in which an increase in body fat promotes adipose tissue dysfunction and abnormal fat mass resulting in adverse metabolic, biomechanical, and psychosocial health consequences-negatively impact female fertility. Adverse conception outcomes are multifactorial, ranging from poor oocyte quality and implantation issues to miscarriages and fetal health issues. However, with the advent of novel pharmacologic agents, significant weight loss can be achieved, improving the chances of healthy pregnancies, and their use should be considered during periconceptual counseling.
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Center for Reproducible Science, University of Zurich, Zurich, Switzerland.
Background: Animal systematic reviews are critical to inform translational research. Despite their growing popularity, there is a notable lack of information on their quality, scope, and geographical distribution over time. Addressing this gap is important to maintain their effectiveness in fostering medical advancements.
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BMC Med Inform Decis Mak
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The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China.
Background: The diagnosis and treatment of epilepsy continue to face numerous challenges, highlighting the urgent need for the development of rapid, accurate, and non-invasive methods for seizure detection. In recent years, advancements in the analysis of electroencephalogram (EEG) signals have garnered widespread attention, particularly in the area of seizure recognition.
Methods: A novel hybrid deep learning approach that combines feature fusion for efficient seizure detection is proposed in this study.
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