The content of angiogenin in human milk and dairy produce for feeding of children of the first year of life is investigated. It is revealed, that the highest concentration of angiogenin in human milk takes place in colostric period (18.00 +/- 0.72 mg/l). During the subsequent time of lactation the concentration of angiogenin keeps at a level 2.00 +/- 0.06 mg/l. In products of infant's feeding the angiogenin either was absent, or its concentration was much lower, than in breast milk.
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Metabolites
January 2025
Department of Nutrition, University of California, Davis, CA 95616, USA.
Metabolic profiling of human milk (HM) is indispensable for elucidating mother-milk-infant relationships. We evaluated the Biocrates MxP Quant 500 assay for HM-targeted metabolomics (106 small molecules, 524 lipids) and analyzed in a feasibility test HM from apparently healthy Brazilian mothers (A: 2-8, B: 28-50, C: 88-119 days postpartum, n = 25). Of the 630 possible signatures detectable with this assay, 506 were above the limits of detection in an HM-pool (10 µL) used for assay evaluation, 12 of them above the upper limit of quantitation.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
January 2025
MyMilk Laboratories Ltd. Herzliya, Herzliya, Israel.
Background: Human milk electrolytes are known biomarkers of stages of lactation in the first weeks after birth. However, methods for measuring milk electrolytes are available only in laboratory or expert settings. A small handheld milk sensing device (Mylee) capable of determining on-site individual secretory activation progress from sensing the conductivity of a tiny milk specimen was developed.
View Article and Find Full Text PDFAnn Nutr Metab
January 2025
Department of Paediatrics, Medical University of Warsaw, Warsaw, Poland.
Background: The gut microbiota, or microbiome, is essential for human health. Early-life factors such as delivery mode, diet, and antibiotic use shape its composition, impacting both short- and long-term health outcomes. Dysbiosis, or alterations in the gut microbiota, is linked to conditions such as allergies, asthma, obesity, diabetes, inflammatory bowel disease, and necrotizing enterocolitis in preterm infants.
View Article and Find Full Text PDFJMIR Res Protoc
January 2025
School of Human Nutrition, McGill University, Sainte-Anne-de-Bellevue, QC, Canada.
Background: The 2019 Canada's Food Guide provides universal recommendations to individuals aged ≥2 years. However, the extent to which these recommendations are appropriate for older adults is unknown. Although ideal, conducting a large randomized controlled trial is unrealistic in the short term.
View Article and Find Full Text PDFHypertens Res
January 2025
Department of Precision Nutrition for Dairy Foods, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
The prevalence of hypertension in Japan remains high, owing to the high salt content of the typical Japanese diet. Dairy-based foods may reduce blood pressure and hypertension risk. However, dairy consumption is low in Japan, and the relationships between dairy intake and blood pressure or the mechanisms by which dairy products affect blood pressure are not fully understood.
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