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Therapeutic proteins are in high demand due to their significant potential, driving continuous market growth. However, a critical concern for therapeutic proteins is their ability to trigger an immune response, while some treatments rely on this response for their therapeutic effect. Therefore, to assess the efficacy and safety of the drug, it is pivotal to determine its immunogenicity potential.
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The novel HLA-C*03:689 allele differs from HLA-C*03:03:01:01 by two nucleotide substitutions in codons 81 and 82 in exon 2.
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