The article has analyzed the main development and improvement stages of medical support of high-altitude flight safety. Test results of a full-scale model of the on-board active flight-safety system [symbol: see text]-2 have been given. There have been formulated prospective trends of further studies of the complex system development of crew-life support, widespread use of computer-aided technologies, as well as practical introduction of rehabilitating hypoxy-based trainings in order to increase in the pilot organism functional reserves.
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