Background: Neurocysticercosis is the CNS involvement caused by Taenia solium larvae and the most frequent cerebral parasitation. It has a cosmopolitan distribution but endemic in the low income countries. The paper analizes the geographic origin, clinical characteristics of patients and the diagnostic and therapeutic modalities.
Patients And Method: Retrospective revision of clinical files in patients with the diagnosis of neurocysticercosis between the period January 1990 to March 2000.
Results: Ten patients were included of which only one was of Spanish nationality. The others were immigrants or travellers to Central/South America (7), Africa (1) and South East Asia (1). Nine patients presented with convulsive crisis, generalized in 7 and 3 cases suffered headaches. The diagnosis was obtained through biopsy technique (3 cases) and the rest through CT scan or MR and serology. ELISA specific serology was positive in 60% of cases. Eight patients were treated with praziquantel or albendazol solely with good clinical evolution.
Conclusions: Neurocysticercosis is prevalent among the immigrant population and in our case imported mostly from Latin America. Diagnosis is reached through imaging and serological techniques. Treatment with praziquantel or albendazol improves the clinical picture and controls the convulsive crisis.
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http://dx.doi.org/10.1016/s0025-7753(01)71790-3 | DOI Listing |
This study aims to determine the factors associated with mortality and neurodevelopmental morbidity in patients with Maple Syrup Urine Disease (MSUD) seen at a tertiary hospital in the Philippines during a 10-year period. The medical records of patients diagnosed with MSUD seen at Philippine General Hospital (PGH) from 2010 to 2019 were reviewed. Socioeconomic, healthcare, and clinical factors were determined.
View Article and Find Full Text PDFExp Neurol
December 2024
Neuroscience Department, U.S. Army Medical Research Institute of Chemical Defense (USAMRICD), Aberdeen Proving Ground, MD, United States of America. Electronic address:
Exposure to organophosphorus nerve agents irreversibly inhibits acetylcholinesterase and may lead to cholinergic crisis and seizures. Although benzodiazepines are the standard of care after nerve agent-induced status epilepticus, when treatment is delayed for up to 30 min or more, refractory status epilepticus can develop. Adult male rodents are often utilized for evaluation of therapeutic efficacy against nerve agent exposure.
View Article and Find Full Text PDFBiomed Phys Eng Express
November 2024
Edmond and Lily Safra International Institute of Neurosciences, Santos Dumont Institute, 59288-899 Macaiba, Brazil.
This study proposes a closed-loop brain-machine interface (BMI) based on spinal cord stimulation to inhibit epileptic seizures, applying a semi-supervised machine learning approach that learns from Local Field Potential (LFP) patterns acquired on the pre-ictal (preceding the seizure) condition.LFP epochs from the hippocampus and motor cortex are band-pass filtered from 1 to 13 Hz, to obtain the time-frequency representation using the continuous Wavelet transform, and successively calculate the phase lock values (PLV). As a novelty, the-score-based PLV normalization using both modified-means and Davies-Bouldin's measure for clustering is proposed here.
View Article and Find Full Text PDFJ Neuroinflammation
November 2024
Department of Molecular Biosciences, Davis, School of Veterinary Medicine, University of California, Davis, CA, 95616, USA.
Acute intoxication with cholinesterase inhibiting organophosphates (OP) can produce life-threatening cholinergic crisis and status epilepticus (SE). Survivors often develop long-term neurological consequences, including spontaneous recurrent seizures (SRS) and impaired cognition. Numerous studies implicate OP-induced neuroinflammation as a pathogenic mechanism contributing to these chronic sequelae; however, little is known about the inflammatory phenotype of innate immune cells in the brain following acute OP intoxication.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Departamento de Ciencias Basicas Medicas, Facultad de Salud, Universidad Icesi, Cali, Colombia.
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